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Metastatic Choriocarcinoma to the Breast: Appearance on Mammography and Doppler Sonography

Naveen Kalra1, Vijayanadh Ojili1, Madhu Gulati1, G. R. V. Prasad2, Kim Vaiphei3 and Sudha Suri1

1 Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, PGIMER, Sector 12, Chandigarh 160012, India.
2 Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
3 Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.



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  		Fig. 1A. —27-year-old woman who presented with a slow-growing, painless lump in right breast. Mammograms of right breast, craniocaudal (A) and oblique (B) views, show large (6.5 x 6.0 x 5.0 cm) well-defined, lobulated, high-density mass in lower inner quadrant of breast. No focus of calcification or surrounding architectural distortion is present.

 


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  		Fig. 1B. —27-year-old woman who presented with a slow-growing, painless lump in right breast. Mammograms of right breast, craniocaudal (A) and oblique (B) views, show large (6.5 x 6.0 x 5.0 cm) well-defined, lobulated, high-density mass in lower inner quadrant of breast. No focus of calcification or surrounding architectural distortion is present.

 


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  		Fig. 1C. —27-year-old woman who presented with a slow-growing, painless lump in right breast. Sonogram of right breast shows well-defined, lobulated, hypoechoic solid mass. No posterior acoustic shadowing or calcification is seen within mass.

 


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  		Fig. 1D. —27-year-old woman who presented with a slow-growing, painless lump in right breast. Power Doppler sonogram of mass lesion shows presence of multiple intralesional vascular channels.

 


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  		Fig. 1E. —27-year-old woman who presented with a slow-growing, painless lump in right breast. Spectral trace of tumor vessel shows high-impedance flow with absent diastolic flow.

 


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  		Fig. 1F. —27-year-old woman who presented with a slow-growing, painless lump in right breast. Photomicrograph of breast tumor shows two types of cells—that is, mononuclear and multinuclear cells with abundant cytoplasm and prominent nucleoli. (H and E, x240)

 


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  		Fig. 1G. —27-year-old woman who presented with a slow-growing, painless lump in right breast. Photomicrograph shows positivity for HCG antibody, seen as brownish discoloration of cytoplasm. (peroxidase-antiperoxidase, x450)

 

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