Pancreatoblastoma in an Adult Woman: Sonography, CT, and Dynamic Gadolinium-Enhanced MRI Features
Joshua L. Rosebrook1,
Jonathan N. Glickman2 and
Koenraad J. Mortele1
1 Division of Abdominal Imaging and Intervention, Department of Radiology,
Brigham and Women's Hospital, Harvard Medical School, 75 Francis St., Boston,
MA 02115.
2 Department of Pathology, Brigham and Women's Hospital, Harvard Medical School,
Boston, MA 02115.

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Fig. 1A. 29-year-old woman with pancreatoblastoma. Contrast-enhanced
axial CT image shows a well-defined mass (white arrow) with cystic
and enhancing solid components in the body of the pancreas.
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Fig. 1B. 29-year-old woman with pancreatoblastoma. Sonographic image
of the pancreas body shows a well-defined, hypoechoic mass (white
arrow) and hyperechoic rim demonstrating Doppler flow.
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Fig. 1C. 29-year-old woman with pancreatoblastoma. T2-weighted image
shows pancreatic mass with a 3-mm-thick low signal rim (black arrow)
and high signal center (white arrow), indicating a cystic
component.
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Fig. 1D. 29-year-old woman with pancreatoblastoma. Unenhanced fat
saturated T1-weighted image shows pancreatic mass with intermediate signal rim
(black arrow) and low to intermediate signal intensity centrally
(white arrow).
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Fig. 1E. 29-year-old woman with pancreatoblastoma. Dynamic
contrast-enhanced fat saturated T1-weighted images in arterial (E),
portal (F), and equilibrium phases (G) show early and persistent
enhancement within rim of pancreatic mass. Central portion of mass does not
enhance.
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Fig. 1F. 29-year-old woman with pancreatoblastoma. Dynamic
contrast-enhanced fat saturated T1-weighted images in arterial (E),
portal (F), and equilibrium phases (G) show early and persistent
enhancement within rim of pancreatic mass. Central portion of mass does not
enhance.
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Fig. 1G. 29-year-old woman with pancreatoblastoma. Dynamic
contrast-enhanced fat saturated T1-weighted images in arterial (E),
portal (F), and equilibrium phases (G) show early and persistent
enhancement within rim of pancreatic mass. Central portion of mass does not
enhance.
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Fig. 1H. 29-year-old woman with pancreatoblastoma. Time-intensity
curves of the enhancement pattern show the rim of the mass and demonstrate
early and persistent enhancement more than normal pancreatic parenchyma, with
little enhancement centrally.
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Fig. 1I. 29-year-old woman with pancreatoblastoma. Gross photograph of
tumor shows a well-circumscribed solid mass (arrow) with central
necrosis.
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Fig. 1J. 29-year-old woman with pancreatoblastoma. Photomicrograph of
viable portion of tumor shows tumor cells arranged in nests and trabeculae
with focal glandular features (arrow). (H and E, x 100)
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Copyright © 2005 by the American Roentgen Ray Society.