Persistent Foreign Body Reaction Around Inguinal Mesh Prostheses: A Potential Pitfall of FDG PET
Nicolas Aide1,
Jean-François Deux2,
Iliana Peretti1,
Laurence Mabille3,
Jacques Mandet4,
Patrice Callard5 and
Jean-Noël Talbot1
1 Hôpitaux de Paris PET Center, Hôpital Tenon, 4 rue de la Chine,
75020, Paris, France.
2 Department of Radiology, Hôpital Tenon, Paris, France.
3 Paris Nord PET Center, Sarcelles, France.
4 Department of Oncology, Institut Gustave Roussy, Villejuif, France.
5 Department of Pathology, Hôpital Tenon, Paris, France.

View larger version (70K):
[in a new window]
|
Fig. 1A. 55-year-old woman (patient 1) with axillary recurrence of
cervical cancer. Patient underwent left inguinal hernia repair with
polytetrafluoroethylene mesh prosthesis 3 years earlier. FDG PET images
confirm axillary and thoracic recurrence (solid arrow, A) and
reveal suspicious focus in left groin (dotted arrow, A) and on
transverse slice B (arrowhead) (SUV max = 2.8).
|
|

View larger version (56K):
[in a new window]
|
Fig. 1B. 55-year-old woman (patient 1) with axillary recurrence of
cervical cancer. Patient underwent left inguinal hernia repair with
polytetrafluoroethylene mesh prosthesis 3 years earlier. FDG PET images
confirm axillary and thoracic recurrence (solid arrow, A) and
reveal suspicious focus in left groin (dotted arrow, A) and on
transverse slice B (arrowhead) (SUV max = 2.8).
|
|

View larger version (111K):
[in a new window]
|
Fig. 1C. 55-year-old woman (patient 1) with axillary recurrence of
cervical cancer. Patient underwent left inguinal hernia repair with
polytetrafluoroethylene mesh prosthesis 3 years earlier. CT scan reveals
nodular hyperattenuating lesion (arrow) next to pelvic parietal wall,
which is consistent with FDG focus and corresponds to mesh prosthesis.
|
|

View larger version (69K):
[in a new window]
|
Fig. 1D. 55-year-old woman (patient 1) with axillary recurrence of
cervical cancer. Patient underwent left inguinal hernia repair with
polytetrafluoroethylene mesh prosthesis 3 years earlier. Image from second PET
study performed after chemotherapy shows complete metabolic response of cancer
foci but no change in the inguinal focus (dotted arrow) (maximum
standardized uptake value [SUVmax] = 2.9).
|
|

View larger version (60K):
[in a new window]
|
Fig. 1E. 55-year-old woman (patient 1) with axillary recurrence of
cervical cancer. Patient underwent left inguinal hernia repair with
polytetrafluoroethylene mesh prosthesis 3 years earlier. Image from third PET
study performed for suspected recurrence confirms axillary recurrence
(solid arrow) while inguinal focus (dotted arrow) remains
steady (SUVmax = 2.8).
|
|

View larger version (52K):
[in a new window]
|
Fig. 1F. 55-year-old woman (patient 1) with axillary recurrence of
cervical cancer. Patient underwent left inguinal hernia repair with
polytetrafluoroethylene mesh prosthesis 3 years earlier. PET/CT image reveals
FDG focus (arrow) precisely located at external part of
hyperattenuating lesion of abdominal wall. Several biopsies were performed
under echographic guidance and revealed foreign body reaction with no
neoplastic cells.
|
|

View larger version (94K):
[in a new window]
|
Fig. 1G. 55-year-old woman (patient 1) with axillary recurrence of
cervical cancer. Patient underwent left inguinal hernia repair with
polytetrafluoroethylene mesh prosthesis 3 years earlier. T1-weighted MR image
shows slightly hyperintense ill-defined lesion (arrow) in abdominal
wall after administration of gadolinium.
|
|

View larger version (67K):
[in a new window]
|
Fig. 2A. 75-year-old man (patient 2) referred to FDG PET for liver
recurrence of rectal cancer. This patient underwent bilateral inguinal hernia
repairs with mesh prostheses (polypropylene) 10 years (right side) and 1 year
(left side) earlier. PET image reveals bilateral areas of intense FDG uptake
(dotted arrows) in anterior part of pelvis. Maximum standardized
uptake values (SUVmax) of liver focus (solid arrow) and
right and left pelvic foci were 8.9, 5.7, and 4.5, respectively.
|
|

View larger version (144K):
[in a new window]
|
Fig. 2B. 75-year-old man (patient 2) referred to FDG PET for liver
recurrence of rectal cancer. This patient underwent bilateral inguinal hernia
repairs with mesh prostheses (polypropylene) 10 years (right side) and 1 year
(left side) earlier. CT scan (B) shows that tissue lesion
(arrowhead, B) located on right side of anterior wall of
bladder is consistent with one of FDG foci (arrowhead, C) on
PET image.
|
|

View larger version (53K):
[in a new window]
|
Fig. 2C. 75-year-old man (patient 2) referred to FDG PET for liver
recurrence of rectal cancer. This patient underwent bilateral inguinal hernia
repairs with mesh prostheses (polypropylene) 10 years (right side) and 1 year
(left side) earlier. CT scan (B) shows that tissue lesion
(arrowhead, B) located on right side of anterior wall of
bladder is consistent with one of FDG foci (arrowhead, C) on
PET image.
|
|

View larger version (64K):
[in a new window]
|
Fig. 2D. 75-year-old man (patient 2) referred to FDG PET for liver
recurrence of rectal cancer. This patient underwent bilateral inguinal hernia
repairs with mesh prostheses (polypropylene) 10 years (right side) and 1 year
(left side) earlier. Image from second PET study performed after chemotherapy
followed by surgery (right hepatectomy) shows same pelvic foci
(arrows) (SUVmax of right focus = 5.9, SUVmax
of left focus = 4.5).
|
|

View larger version (63K):
[in a new window]
|
Fig. 3A. 50-year-old man (patient 3) referred to FDG PET after
neoadjuvant chemotherapy for non-small cell carcinoma in right lung. This
patient underwent treatment of bilateral inguinal hernia with
polytetrafluoroethylene mesh prosthesis implant 5 years earlier. PET image
shows solitary focus (solid arrow, SUVmax = 7.1) in right
lung and reveals less intense foci (dotted arrows, SUVmax = 4.1) in
pelvis.
|
|

View larger version (113K):
[in a new window]
|
Fig. 3B. 50-year-old man (patient 3) referred to FDG PET after
neoadjuvant chemotherapy for non-small cell carcinoma in right lung. This
patient underwent treatment of bilateral inguinal hernia with
polytetrafluoroethylene mesh prosthesis implant 5 years earlier. CT scan was
thought to show normal findings at time of PET examination, but retrospective
analysis revealed slightly hyperattenuating area (arrow) in anterior
abdominal wall that was consistent with one of FDG foci.
|
|

CiteULike
Complore
Connotea
Del.icio.us
Digg
Reddit
Technorati What's this?
Copyright © 2005 by the American Roentgen Ray Society.