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Micro-CT Arthrography: A Pilot Study for the Ex Vivo Visualization of the Rat Knee Joint

Frank W. Roemer1,2, Andreas Mohr1,3, John A. Lynch1, Margarita D. Meta1, Ali Guermazi1 and Harry K. Genant1

1 Osteoporosis and Arthritis Research Group, Department of Radiology, University of California at San Francisco, San Francisco, CA 94117.



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  		Fig. 1A. —Measurement of retropatellar cartilage thickness and visualization of intrinsic joint structures in rat using micro-CT arthrography. Micro-CT arthrographic image shows three locations for measurement of retropatellar cartilage thickness in axial plane.

 


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  		Fig. 1B. —Measurement of retropatellar cartilage thickness and visualization of intrinsic joint structures in rat using micro-CT arthrography. Micro-CT arthrographic image shows three locations for measurement of retropatellar cartilage thickness in axial plane that are labeled UP, MID, and LOW.

 


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  		Fig. 1C. —Measurement of retropatellar cartilage thickness and visualization of intrinsic joint structures in rat using micro-CT arthrography. Sagittal reconstruction of micro-CT arthrographic images shows anterior cruciate ligament (black arrow), infrapatellar plica (arrowhead), and infrapatellar fat pad (white arrow).

 


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  		Fig. 1D. —Measurement of retropatellar cartilage thickness and visualization of intrinsic joint structures in rat using micro-CT arthrography. Axial reconstruction of micro-CT arthrographic images shows distinct meniscofemoral ligaments (white arrows). Popliteal tendon (black arrow) is visualized laterally

 


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  		Fig. 2. —Micro-CT arthrography was used to produce 3D surface reconstruction of structural analysis of cancellous bone within tibial epiphysis of rat viewed from above. Virtual light source is located at right upper corner of image.

 

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