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Determination of Splenomegaly by CT: Is There a Place for a Single Measurement?

Alexandre S. Bezerra1, Giuseppe D'Ippolito2, Salomão Faintuch3, Jacob Szejnfeld2 and Muneeb Ahmed3

1 Universidade Católica de Brasília-Campus I, Curso de Medicina, EPCT QS 7 Lote 1, Taguatinga, Distrito Federal, Brazil, 71966-700.
2 Department of Diagnostic Imaging, Federal University of São Paulo, São Paulo, Brazil.
3 Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.



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  		Fig. 1. —Example of method used for tracing outline of spleen. Workstation then provides total area enclosed and this area is multiplied by scan width to obtain partial volume of spleen on each image. All partial volumes are summed to obtain total splenic volume.

 


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  		Fig. 2. —Example of measurement of largest width (W) of spleen, greatest thickness at section where W was determined (T1), and thickness at midpoint of section where W was determined (T2).

 


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  		Fig. 3. —Scatterplot of data shows high degree of correlation between length (L) on y-axis and splenic volume (cm3) on x-axis across range of values. Regression line is superimposed. Correlation coefficient was 0.816.

 


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  		Fig. 4. —Scatterplot of data shows high degree of correlation between index 3 (L x W x T3) on y-axis and splenic volume (cm3) on x-axis across a range of values. Regression line is superimposed. Correlation coefficient was 0.95.

 

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