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Can Doppler Sonography Grade the Severity of Hepatitis C-Related Liver Disease?

Adrian K. P. Lim1, Nayna Patel1,2, Robert J. Eckersley1, Yu-Ting Kuo1,3, Robert D. Goldin4, Howard C. Thomas5, David O. Cosgrove1, Simon D. Taylor-Robinson1,2 and Martin J. K. Blomley1

1 Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, Du Cane Rd., London W12 0HS, UK.
2 Department of Medicine A, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London W12 0HS, UK.
3 Department of Medical Imaging, Kaohsiung Medical University, Kaohsiung, Taiwan.
4 Department of Histopathology, Faculty of Medicine, Imperial College London, St. Mary's Hospital, Praed St., London W12 1NY, UK.
5 Department of Medicine, Faculty of Medicine, Imperial College London, St. Mary's Hospital, London W12 1NY, UK.



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  		Fig. 1A. —Color Doppler sonograms of 45-year-old man with hepatitis C virus-related disease. Images show main portal vein velocity measurement (A) and hepatic arterial velocity measurement where it crosses portal vein (B).

 


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  		Fig. 1B. —Color Doppler sonograms of 45-year-old man with hepatitis C virus-related disease. Images show main portal vein velocity measurement (A) and hepatic arterial velocity measurement where it crosses portal vein (B).

 


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  		Fig. 2A. —Doppler sonograms of 34-year-old woman with hepatitis C virus-related disease. Images show portal vein diameter (A) and portal vein circumference (B).

 


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  		Fig. 2B. —Doppler sonograms of 34-year-old woman with hepatitis C virus-related disease. Images show portal vein diameter (A) and portal vein circumference (B).

 


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  		Fig. 3A. —Doppler sonograms of patients with hepatitis C virus-related disease show examples of wave phasicity patterns observed in hepatic veins. Image of 28-year-old man shows triphasic waveform.

 


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  		Fig. 3B. —Doppler sonograms of patients with hepatitis C virus-related disease show examples of wave phasicity patterns observed in hepatic veins. Image of 56-year-old man shows biphasic waveform.

 


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  		Fig. 3C. —Doppler sonograms of patients with hepatitis C virus-related disease show examples of wave phasicity patterns observed in hepatic veins. Image of 43-year-old woman shows monophasic waveform.

 


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  		Fig. 4. —Graph illustrates mean splenic length in centimeters (...) ± 2 SEs (horizontal lines) for three groups categorized by severity of hepatitis.

 

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