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MDCT Urography of Upper Tract Urothelial Neoplasms

Elaine M. Caoili1, Richard H. Cohan1, Prasuna Inampudi1, James H. Ellis1, Rajal B. Shah2, Gary J. Faerber3 and James E. Montie3

1 Department of Radiology, University of Michigan Health System, B1-132 Taubman Center 0302, 1500 E Medical Center Dr., Ann Arbor, MI 48109-0302.
2 Department of Pathology, University of Michigan Health System, Ann Arbor, MI 48109-0302.
3 Department of Urology, University of Michigan Health System, Ann Arbor, MI 48109-0302.



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Fig. 1. 59-year-old man with papillary transitional cell carcinoma of right collecting system. Contrast-enhanced axial MDCT scan shows large (> 5 mm) mass (arrow) in right renal pelvis. Tumor stage is not available on this patient, who was diagnosed only with endoscopic biopsy.

 


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Fig. 2A. 74-year-old man with unstaged papillary transitional cell carcinoma of right collecting system. Contrast-enhanced axial MDCT scan shows upper pole infundibular urothelial wall thickening (arrows) that represents cancer.

 


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Fig. 2B. 74-year-old man with unstaged papillary transitional cell carcinoma of right collecting system. Lesion (arrow) is less well depicted on average-intensity-projection image.

 


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Fig. 3A. 65-year-old man after right nephrectomy for transitional cell carcinoma with unstaged papillary carcinoma of left collecting system. Excretory phase axial MDCT scan viewed with wide window setting shows two small (≤ 5 mm) masses in left intrarenal collecting system (arrows). Lesions were not seen when standard soft-tissue window setting was used.

 


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Fig. 3B. 65-year-old man after right nephrectomy for transitional cell carcinoma with unstaged papillary carcinoma of left collecting system. Volume-rendered image is unremarkable and also does not show tumor.

 


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Fig. 4A. 67-year-old man with flat carcinoma in situ of left distal ureter. Excretory phase axial MDCT scan (A) and volume-rendered image (B) show poor opacification of left distal ureteral segment (arrow). Urothelial cancer was missed on both prospective and retrospective review. Banding artifact overlying renal parenchyma on volume-rendered image is due to injection pump implant.

 


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Fig. 4B. 67-year-old man with flat carcinoma in situ of left distal ureter. Excretory phase axial MDCT scan (A) and volume-rendered image (B) show poor opacification of left distal ureteral segment (arrow). Urothelial cancer was missed on both prospective and retrospective review. Banding artifact overlying renal parenchyma on volume-rendered image is due to injection pump implant.

 


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Fig. 5A. 76-year-old woman with noninvasive (stage Ta) papillary transitional cell carcinomas of left collecting system. Excretory phase axial MDCT image with wide window setting of left renal pelvis shows small (≤ 5 mm) masses (arrows).

 


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Fig. 5B. 76-year-old woman with noninvasive (stage Ta) papillary transitional cell carcinomas of left collecting system. Lesions are much more difficult to identify on same image using soft-tissue window setting.

 


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Fig. 6A. 56-year-old man with papillary transitional cell carcinoma of left collecting system, which invades renal parenchyma (stage T3). Standard excretory phase axial MDCT image (A) and maximum-intensity-projection image (B) of left upper pole show large infundibular and caliceal mass (arrows).

 


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Fig. 6B. 56-year-old man with papillary transitional cell carcinoma of left collecting system, which invades renal parenchyma (stage T3). Standard excretory phase axial MDCT image (A) and maximum-intensity-projection image (B) of left upper pole show large infundibular and caliceal mass (arrows).

 


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Fig. 7. 73-year-old man with high-grade papillary transitional cell carcinoma of right collecting system and invasion of lamina propria (stage T1). Excretory phase axial CT image of right renal pelvis shows urothelial thickening (arrows). Thickening could not be identified on any 3D image, each of which showed only normal-appearing renal pelvis.

 


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Fig. 8A. 76-year-old man after radical cystectomy for bladder carcinoma. Patient has high-grade papillary transitional cell carcinoma of left collecting system and invasion into renal parenchyma (stage T3). Excretory phase axial MDCT image of left kidney shows large infiltrative mass in upper pole (arrows).

 


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Fig. 8B. 76-year-old man after radical cystectomy for bladder carcinoma. Patient has high-grade papillary transitional cell carcinoma of left collecting system and invasion into renal parenchyma (stage T3). Although maximum-intensity-projection image shows distortion of collecting system from upper pole tumor (arrow), full extent of tumor is not determined and renal parenchymal invasion cannot be identified.

 

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