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Variability of Repeated Coronary Artery Calcium Measurements by 16-MDCT with Retrospective Reconstruction

Jun Horiguchi1, Hideya Yamamoto2, Yuji Akiyama1, Nobuhiko Hirai1, Kazushi Marukawa3, Hiroshi Fukuda1 and Katsuhide Ito3

1 Department of Clinical Radiology, Hiroshima University Hospital, 1-2-3, Kasumi-cho, Minami-ku, Hiroshima 734-8551, Japan.
2 Department of Molecular and Internal Medicine, Division of Clinical Medical Science, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.
3 Department of Radiology, Division of Medical Intelligence and Informatics, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima Univerisity, Hiroshima, Japan.



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Fig. 1A. Scatterplots of Agatston scores for scans 1 and 2 for electron beam CT (EBCT) and for three MDCT protocols. Scatterplot of Agatston scores for EBCT shows linear correlation follows an equation: scan 2 = 51.3 + 0.86 x scan 1 (r2 = 0.961).

 


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Fig. 1B. Scatterplots of Agatston scores for scans 1 and 2 for electron beam CT (EBCT) and for three MDCT protocols. Scatterplot of Agatston scores for 1.25-mm MDCT shows linear correlation follows an equation: scan 2 = -3.0 + 1.05 x scan 1 (r2 = 0.966).

 


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Fig. 1C. Scatterplots of Agatston scores for scans 1 and 2 for electron beam CT (EBCT) and for three MDCT protocols. Scatterplot of Agatston scores for 2.5 mm/2.5 mm MDCT shows linear correlation follows an equation: scan 2 = -0.8 + 1.06 x scan 1 (r2 = 0.981).

 


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Fig. 1D. Scatterplots of Agatston scores for scans 1 and 2 for electron beam CT (EBCT) and for three MDCT protocols. Scatterplot of Agatston scores for 2.5 mm/1.25 mm MDCT shows linear correlation follows an equation: scan 2 = -22.1 + 1.08 x scan 1 (r2 = 0.991).

 


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Fig. 2A. 44-year-old asymptomatic man (heart rate, 68 beats per minute). Transaxial images from first electron beam CT (EBCT) (A), first 1.25-mm-thickness MDCT (B), and first 2.5-mm-thickness MDCT show heart. Calcium is not detected on EBCT and 2.5-mm-thickness MDCT. Calcium in left main coronary artery is detected on 1.25-mm-thickness MDCT.

 


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Fig. 2B. 44-year-old asymptomatic man (heart rate, 68 beats per minute). Transaxial images from first electron beam CT (EBCT) (A), first 1.25-mm-thickness MDCT (B), and first 2.5-mm-thickness MDCT show heart. Calcium is not detected on EBCT and 2.5-mm-thickness MDCT. Calcium in left main coronary artery is detected on 1.25-mm-thickness MDCT.

 


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Fig. 2C. 44-year-old asymptomatic man (heart rate, 68 beats per minute). Transaxial images from first electron beam CT (EBCT) (A), first 1.25-mm-thickness MDCT (B), and first 2.5-mm-thickness MDCT show heart. Calcium is not detected on EBCT and 2.5-mm-thickness MDCT. Calcium in left main coronary artery is detected on 1.25-mm-thickness MDCT.

 


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Fig. 3A. 69-year-old man complaining of anterior chest pain (heart rate, 55 beats per minute). Transaxial images from first electron beam CT (EBCT) (A), second EBCT (B), first 1.25-mm-thickness MDCT (C), second 1.25-mm-thickness MDCT (D), first 2.5-mm-thickness MDCT (E), and second 2.5-mm-thickness MDCT (F) show heart. Calcium in right coronary artery is most clearly seen on 1.25-mm-thickness MDCT. On EBCT, calcium is detected on first scan and is not detected on second scan.

 


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Fig. 3B. 69-year-old man complaining of anterior chest pain (heart rate, 55 beats per minute). Transaxial images from first electron beam CT (EBCT) (A), second EBCT (B), first 1.25-mm-thickness MDCT (C), second 1.25-mm-thickness MDCT (D), first 2.5-mm-thickness MDCT (E), and second 2.5-mm-thickness MDCT (F) show heart. Calcium in right coronary artery is most clearly seen on 1.25-mm-thickness MDCT. On EBCT, calcium is detected on first scan and is not detected on second scan.

 


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Fig. 3C. 69-year-old man complaining of anterior chest pain (heart rate, 55 beats per minute). Transaxial images from first electron beam CT (EBCT) (A), second EBCT (B), first 1.25-mm-thickness MDCT (C), second 1.25-mm-thickness MDCT (D), first 2.5-mm-thickness MDCT (E), and second 2.5-mm-thickness MDCT (F) show heart. Calcium in right coronary artery is most clearly seen on 1.25-mm-thickness MDCT. On EBCT, calcium is detected on first scan and is not detected on second scan.

 


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Fig. 3D. 69-year-old man complaining of anterior chest pain (heart rate, 55 beats per minute). Transaxial images from first electron beam CT (EBCT) (A), second EBCT (B), first 1.25-mm-thickness MDCT (C), second 1.25-mm-thickness MDCT (D), first 2.5-mm-thickness MDCT (E), and second 2.5-mm-thickness MDCT (F) show heart. Calcium in right coronary artery is most clearly seen on 1.25-mm-thickness MDCT. On EBCT, calcium is detected on first scan and is not detected on second scan.

 


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Fig. 3E. 69-year-old man complaining of anterior chest pain (heart rate, 55 beats per minute). Transaxial images from first electron beam CT (EBCT) (A), second EBCT (B), first 1.25-mm-thickness MDCT (C), second 1.25-mm-thickness MDCT (D), first 2.5-mm-thickness MDCT (E), and second 2.5-mm-thickness MDCT (F) show heart. Calcium in right coronary artery is most clearly seen on 1.25-mm-thickness MDCT. On EBCT, calcium is detected on first scan and is not detected on second scan.

 


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Fig. 3F. 69-year-old man complaining of anterior chest pain (heart rate, 55 beats per minute). Transaxial images from first electron beam CT (EBCT) (A), second EBCT (B), first 1.25-mm-thickness MDCT (C), second 1.25-mm-thickness MDCT (D), first 2.5-mm-thickness MDCT (E), and second 2.5-mm-thickness MDCT (F) show heart. Calcium in right coronary artery is most clearly seen on 1.25-mm-thickness MDCT. On EBCT, calcium is detected on first scan and is not detected on second scan.

 


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Fig. 4A. 69-year-old obese man complaining of anterior chest pain (heart rate, 60 beats per minute). Transaxial electron beam CT (EBCT) image (A), transaxial 1.25-mm-thickness MDCT image (B), and transaxial 2.5-mm-thickness MDCT image (C) show heart. SDs of CT values in region of interest placed in aortic root were measured as 39, 42, and 30 H on EBCT and 1.25- and 2.5-mm-thickness MDCT, respectively. No apparent calcium is found in left coronary artery region. However, hyperdense noise exceeds CT value of 130 H on EBCT and 1.25-mm-thickness MDCT.

 


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Fig. 4B. 69-year-old obese man complaining of anterior chest pain (heart rate, 60 beats per minute). Transaxial electron beam CT (EBCT) image (A), transaxial 1.25-mm-thickness MDCT image (B), and transaxial 2.5-mm-thickness MDCT image (C) show heart. SDs of CT values in region of interest placed in aortic root were measured as 39, 42, and 30 H on EBCT and 1.25- and 2.5-mm-thickness MDCT, respectively. No apparent calcium is found in left coronary artery region. However, hyperdense noise exceeds CT value of 130 H on EBCT and 1.25-mm-thickness MDCT.

 


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Fig. 4C. 69-year-old obese man complaining of anterior chest pain (heart rate, 60 beats per minute). Transaxial electron beam CT (EBCT) image (A), transaxial 1.25-mm-thickness MDCT image (B), and transaxial 2.5-mm-thickness MDCT image (C) show heart. SDs of CT values in region of interest placed in aortic root were measured as 39, 42, and 30 H on EBCT and 1.25- and 2.5-mm-thickness MDCT, respectively. No apparent calcium is found in left coronary artery region. However, hyperdense noise exceeds CT value of 130 H on EBCT and 1.25-mm-thickness MDCT.

 

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