HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Tadamura, E. Articles by Togashi, K. Search for Related Content PubMed PubMed Citation Articles by Tadamura, E. Articles by Togashi, K. Social Bookmarking                      What's this? Hotlight (NEW!) What's Hotlight?

Effectiveness of Delayed Enhanced MRI for Identification of Cardiac Sarcoidosis: Comparison with Radionuclide Imaging

¹ Department of Nuclear Medicine and Diagnostic Imaging, Kyoto University Graduate School of Medicine, 54 Shogoinkawahara, Sakyo-ku, Kyoto 606-8507, Japan.
² Department of Endocrinology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
³ Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

View larger version (135K): [in a new window]   Fig. 1A —52-year-old woman with clinically diagnosed cardiac sarcoidosis. Basal short-axis delayed enhanced MR image depicts delayed enhancement on right ventricular side of septal region (arrows).

View larger version (119K): [in a new window]   Fig. 1B —52-year-old woman with clinically diagnosed cardiac sarcoidosis. Cine MR images obtained at end diastole (B) and end systole (C) for basal short-axis slice show no abnormal wall motion.

View larger version (116K): [in a new window]   Fig. 1C —52-year-old woman with clinically diagnosed cardiac sarcoidosis. Cine MR images obtained at end diastole (B) and end systole (C) for basal short-axis slice show no abnormal wall motion.

View larger version (114K): [in a new window]   Fig. 1D —52-year-old woman with clinically diagnosed cardiac sarcoidosis. Basal short-axis 201Tl SPECT image shows no abnormal perfusion defect. No abnormal 67Ga uptake in heart was observed on 67Ga scintigrams.

View larger version (147K): [in a new window]   Fig. 2A —69-year-old man with clinically diagnosed cardiac sarcoidosis. Basal short-axis delayed enhanced MR image reveals strong transmural hyperenhancement in septal, anterior, and inferior regions (arrows).

View larger version (132K): [in a new window]   Fig. 2B —69-year-old man with clinically diagnosed cardiac sarcoidosis. Cine MR images obtained at end diastole (B) and end systole (C) for basal short-axis slice show wall motion abnormalities in these segments (arrows, C).

View larger version (131K): [in a new window]   Fig. 2C —69-year-old man with clinically diagnosed cardiac sarcoidosis. Cine MR images obtained at end diastole (B) and end systole (C) for basal short-axis slice show wall motion abnormalities in these segments (arrows, C).

View larger version (88K): [in a new window]   Fig. 2D —69-year-old man with clinically diagnosed cardiac sarcoidosis. Basal short-axis 201Tl SPECT image shows perfusion defects in septal, anterior, and inferior regions (arrows), where severe extent of transmural enhancement is seen on delayed enhanced MR images. No abnormal cardiac 67Ga uptake was detected on 67Ga scintigrams.

View larger version (149K): [in a new window]   Fig. 3A —65-year-old woman with histologically diagnosed cardiac sarcoidosis. Basal short-axis delayed enhanced MR image reveals strong transmural enhancement in septal and inferior regions (arrows). Abnormal hyperenhancement is also observed in right ventricular wall (arrowheads).

View larger version (135K): [in a new window]   Fig. 3B —65-year-old woman with histologically diagnosed cardiac sarcoidosis. Cine MR images obtained at end diastole (B) and end systole (C) for basal short-axis slice show wall motion abnormalities in inferior segments (arrows, C).

View larger version (136K): [in a new window]   Fig. 3C —65-year-old woman with histologically diagnosed cardiac sarcoidosis. Cine MR images obtained at end diastole (B) and end systole (C) for basal short-axis slice show wall motion abnormalities in inferior segments (arrows, C).

View larger version (100K): [in a new window]   Fig. 3D —65-year-old woman with histologically diagnosed cardiac sarcoidosis. Basal short-axis 201Tl SPECT image shows perfusion defects in septal and inferior regions (arrows).

View larger version (69K): [in a new window]   Fig. 3E —65-year-old woman with histologically diagnosed cardiac sarcoidosis. Basal short-axis 67Ga SPECT image shows abnormal accumulation of 67Ga mainly in inferior and septal regions (arrows), corresponding to areas with significant transmural hyperenhancement and 201Tl perfusion defects.

View larger version (15K): [in a new window]   Fig. 4 —Number of segments with abnormal delayed enhancement among 17 myocardial segments in 10 patients. Abnormal delayed enhancement was frequently observed in basal septal region.

View larger version (21K): [in a new window]   Fig. 5 —Bar graph shows relationship between transmural extent of delayed gadolinium enhancement and 201Tl perfusion defects. Significant differences were observed in mean percentage of 201Tl perfusion defect score between segments of grades 0 and 1, grades 1 and 2, grades 2 and 3, and grades 3 and 4.

View larger version (21K): [in a new window]   Fig. 6 —Bar graph indicates relationship between transmural extent of delayed gadolinium enhancement and regional wall motion. Significant differences were noted in mean percentage of wall motion score between segments of grades 0 and 1, grades 1 and 2, grades 2 and 3, and grades 3 and 4.

CiteULike

Complore

Connotea

Del.icio.us

Digg

Reddit

Technorati