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Lung Cancer Screening Experience: A Retrospective Review of PET in 22 Non-Small Cell Lung Carcinomas Detected on Screening Chest CT in a High-Risk Population

Rebecca M. Lindell1, Thomas E. Hartman1, Stephen J. Swensen1, James R. Jett2, David E. Midthun2, Mark A. Nathan1 and Val J. Lowe1

1 Department of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN 55905.
2 Department of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905.



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  		Fig. 1A —67-year-old man with two synchronous grade 4 non-small cell lung carcinomas with squamous features in left upper lobe; grade 4 is highest grade. Axial unenhanced CT image at level of aortic arch shows 13-mm irregular solid nodule (arrow) in apicoposterior segment of left upper lobe.

 


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  		Fig. 1B —67-year-old man with two synchronous grade 4 non-small cell lung carcinomas with squamous features in left upper lobe; grade 4 is highest grade. Axial unenhanced CT image at level just above carina shows 10-mm spiculated solid nodule (arrow) in anterior segment of left upper lobe.

 


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  		Fig. 1C —67-year-old man with two synchronous grade 4 non-small cell lung carcinomas with squamous features in left upper lobe; grade 4 is highest grade. Coronal unenhanced PET maximum-intensity-projection image shows that both nodules (arrows) are hypermetabolic.

 


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  		Fig. 2A —68-year-old man with grade 1 bronchioloalveolar cell carcinoma; grade 4 is highest grade. Axial unenhanced CT image at level of top of aortic arch shows 8-mm irregular solid nodule (arrow) in left upper lobe.

 


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  		Fig. 2B —68-year-old man with grade 1 bronchioloalveolar cell carcinoma; grade 4 is highest grade. Coronal unenhanced PET maximum-intensity-projection image does not show nodule seen in A and is interpreted as showing negative findings for lung cancer.

 


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  		Fig. 3A —70-year-old woman with grade 2 adenocarcinoma; grade 4 is highest grade. Axial unenhanced CT image at level of right pulmonary artery shows 8.5-mm spiculated semisolid nodule (arrow) in left upper lobe. Radiolucency within nodule was confirmed to be air bronchogram on additional images (not shown).

 


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  		Fig. 3B —70-year-old woman with grade 2 adenocarcinoma; grade 4 is highest grade. Coronal unenhanced PET image at same level as A shows faint uptake in region of nodule (arrow), but not enough to meet criteria for positive PET findings.

 

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