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Pulmonary Sarcoidosis: Comparison of Findings of Inspiratory and Expiratory High-Resolution CT and Pulmonary Function Tests Between Smokers and Nonsmokers

Hiroshi Terasaki1, Kiminori Fujimoto1, Nestor L. Müller2, Junko Sadohara1, Masafumi Uchida1, Takeharu Koga3, Hisamichi Aizawa3 and Naofumi Hayabuchi1

1 Department of Radiology, Kurume University School of Medicine, 67 Asahimachi, Kurume, Fukuoka 830-0011, Japan.
2 Department of Radiology, Vancouver General Hospital, University of British Columbia, Vancouver, BC, V5Z 1M9 Canada.
3 First Department of Internal Medicine, Kurume University School of Medicine, Kurume, Fukuoka 830-0011, Japan.



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  		Fig. 1A —High-resolution CT images of middle lung zone in 24-year-old woman (nonsmoker) with pulmonary sarcoidosis. Inspiratory CT scan shows bilateral hilar lymphadenopathy (arrows) and peripheral small nodular opacities in middle lobe (arrowheads).

 


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  		Fig. 1B —High-resolution CT images of middle lung zone in 24-year-old woman (nonsmoker) with pulmonary sarcoidosis. Expiratory CT scan reveals air trapping in lower lobes.

 


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  		Fig. 2A —High-resolution CT images of upper lung zone in 65-year-old woman (smoker) with pulmonary sarcoidosis. Inspiratory CT scan shows mild emphysema and scattered small nodular opacities in upper lobes.

 


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  		Fig. 2B —High-resolution CT images of upper lung zone in 65-year-old woman (smoker) with pulmonary sarcoidosis. Expiratory CT scan shows increasing attenuation of bilateral upper lobes; however, air radiolucent areas of emphysema are remaining.

 


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  		Fig. 3A —High-resolution CT images of lower lung zone in 34-year-old man (nonsmoker) with pulmonary sarcoidosis. Inspiratory CT scan shows reticular opacities with architectural distortion. Also noted are patchy ground-glass opacities and patchy air-space consolidation (arrow).

 


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  		Fig. 3B —High-resolution CT images of lower lung zone in 34-year-old man (nonsmoker) with pulmonary sarcoidosis. Expiratory CT scan reveals air trapping in middle lobe and lingula (arrowheads).

 


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  		Fig. 4A —High-resolution CT images of middle lung zone in 29-year-old woman (nonsmoker) with pulmonary sarcoidosis. Inspiratory CT scan shows numerous bilateral small nodules.

 


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  		Fig. 4B —High-resolution CT images of middle lung zone in 29-year-old woman (nonsmoker) with pulmonary sarcoidosis. Expiratory CT scan shows minimal air trapping (arrows) in upper lobes.

 

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