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Comparison of Gadobenate Dimeglumine-Enhanced Dynamic MRI and 16-MDCT for the Detection of Hepatocellular Carcinoma

Young Kon Kim1, Chong Soo Kim1, Gyong Ho Chung1, Young-Min Han1, Sang Yong Lee1, Su Bin Chon1 and Jeong Min Lee2

1 Department of Diagnostic Radiography, Chonbuk National University Hospital and Medical School, Jeonju, South Korea.
2 Department of Radiology and Institute of Radiation Medicine, Seoul National University Hospital, 28, Yongon-dong, Chongno-gu, Seoul 110-744, South Korea.



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Fig. 1A 63-year-old man with pathologically proven hepatocellular carcinoma. Early arterial phase MDCT image shows no visible liver lesion.

 


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Fig. 1B 63-year-old man with pathologically proven hepatocellular carcinoma. Late arterial phase MDCT image shows subtly enhanced nodule in segment V (arrow).

 


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Fig. 1C 63-year-old man with pathologically proven hepatocellular carcinoma. On delayed phase MDCT image, subtle enhancement of nodule in B is shown as slight low attenuation (arrow).

 


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Fig. 1D 63-year-old man with pathologically proven hepatocellular carcinoma. Early arterial phase 3D dynamic MR image after administration of gadobenate dimeglumine shows no visible liver lesion.

 


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Fig. 1E 63-year-old man with pathologically proven hepatocellular carcinoma. Late arterial phase MR image shows brightly enhanced nodule (arrow) at same level as B.

 


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Fig. 1F 63-year-old man with pathologically proven hepatocellular carcinoma. On delayed phase MR image, brightly enhanced nodule shown in E is depicted as low signal intensity (arrow), making the nodule more conspicuous than on CT.

 


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Fig. 2A 61-year-old man with surgically confirmed hepatocellular carcinomas. Late arterial phase MDCT image shows area of subtle low attenuation (arrow) in liver segment V.

 


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Fig. 2B 61-year-old man with surgically confirmed hepatocellular carcinomas. Delayed phase MDCT image also shows area of subtle low attenuation (arrow) in same location as A; this finding was not regarded as true lesion by any of the observers.

 


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Fig. 2C 61-year-old man with surgically confirmed hepatocellular carcinomas. Late arterial phase 3D dynamic MR image after administration of gadobenate dimeglumine shows small enhanced nodule (arrow) in same location as A.

 


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Fig. 2D 61-year-old man with surgically confirmed hepatocellular carcinomas. Equilibrium phase MR image obtained 3 min after contrast injection shows small mass with low signal intensity (arrow); mass is more conspicuous on this image than on B.

 


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Fig. 3A 58-year-old man with surgically confirmed single hepatocellular carcinoma. Late arterial phase MDCT image shows two nodular enhancements in hepatic dome (arrows). Larger lesion was proven to be hepatocellular carcinoma and other was proven to be pseudolesion. These two lesions were correctly interpreted by all observers.

 


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Fig. 3B 58-year-old man with surgically confirmed single hepatocellular carcinoma. Late arterial phase 3D dynamic MR image after administration of gadobenate dimeglumine shows three nodular enhancements in hepatic dome, including hepatocellular carcinoma (large arrow) and pseudolesion (upper small arrow), that were shown on MDCT (A). This pseudolesion was correctly interpreted by all observers, but additional enhancement (lower small arrow) of small pseudolesion was misdiagnosed as a true lesion by all observers.

 

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