Importance of Pretest Probability Score and D-Dimer Assay Before Sonography for Lower Limb Deep Venous Thrombosis
Rathan M. Subramaniam1,2,3,
Tina Chou1,
Rebekah Heath1 and
Robin Allen4
1 Academic and Research Division, Department of Radiology, Waikato Hospital,
Hamilton, New Zealand.
2 Department of Radiology, Waikato Clinical School, University of Auckland,
Hamilton, New Zealand.
3 Present address: Department of Medical Imaging, The Canberra Hospital and the
Australian National University, Canberra, Australia.
4 Department of Haematology, Waikato Hospital, Hamilton, New Zealand.

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Fig. 1 Flow chart shows study outcome of validation phase. Of 103
patients with unlikely pretest probability by Hamilton score and negative
Simplify (Agen Biochemical) D-dimer assay, one patient had isolated calf deep
venous thrombosis (DVT). Numbers refer to numbers of patients.
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Fig. 2 Flow chart shows diagnostic strategy for suspected lower limb
deep venous thrombosis (DVT). Clinically excluding DVT by combining unlikely
probability and negative D-dimer result can lead to a potential saving in
health expenditures and allows timely discharge of patients.
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Copyright © 2006 by the American Roentgen Ray Society.