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Acute Pulmonary Embolism: Correlation of CT Pulmonary Artery Obstruction Index with Blood Gas Values

Zafiria M. Metafratzi1, Miltos P. Vassiliou2, George C. Maglaras2, Froso G. Katzioti1, Stauros H. Constantopoulos1, Afroditi Katsaraki3 and Stauros C. Efremidis1

1 Department of Radiology, University Hospital of Ioannina, Panepistimiou Ave., Ioannina 45500, Greece.
2 Department of Pneumonology, University Hospital of Ioannina, Ioannina 45500, Greece.
3 Department of Statistics, University Hospital of Ioannina, Ioannina 45500, Greece.



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Fig. 1A Scatter diagrams show negative correlation with pulmonary artery obstruction index for 34 studied patients with acute pulmonary embolism. Note negative correlation between pulmonary artery obstruction index and blood gas values. PaO2 (arterial partial pressure of oxygen) (r = –0.33, p = 0.057).

 


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Fig. 1B Scatter diagrams show negative correlation with pulmonary artery obstruction index for 34 studied patients with acute pulmonary embolism. Note negative correlation between pulmonary artery obstruction index and blood gas values. PaCO2 (arterial partial pressure of carbon dioxide) (r = –0.34, p = 0.05).

 


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Fig. 1C Scatter diagrams show negative correlation with pulmonary artery obstruction index for 34 studied patients with acute pulmonary embolism. Note negative correlation between pulmonary artery obstruction index and blood gas values. SaO2 (arterial oxygen saturation) (r = –0.35, p = 0.045).

 


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Fig. 1D Scatter diagrams show negative correlation with pulmonary artery obstruction index for 34 studied patients with acute pulmonary embolism. Note negative correlation between pulmonary artery obstruction index and blood gas values. PAO2–PaO2 (alveolar–arterial difference in partial pressure of oxygen) (r = 0.39, p = 0.02).

 


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Fig. 2A 76-year-old man with multiple large emboli. Coronal multiplanar reconstructions of CT pulmonary angiography performed with 16-MDCT scanner show endoluminal defects (arrows). Patient received pulmonary artery obstruction index of 87.5%, and his blood gas values were PaO2 (arterial partial pressure of oxygen), 43.4 mm Hg; PaCO2 (arterial partial pressure of carbon dioxide), 25.5 mm Hg; SaO2 (arterial oxygen saturation), 82.5%; and PAO2–PaO2 (alveolar–arterial difference in partial pressure of oxygen), 74.7 mm Hg.

 


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Fig. 2B 76-year-old man with multiple large emboli. Coronal multiplanar reconstructions of CT pulmonary angiography performed with 16-MDCT scanner show endoluminal defects (arrows). Patient received pulmonary artery obstruction index of 87.5%, and his blood gas values were PaO2 (arterial partial pressure of oxygen), 43.4 mm Hg; PaCO2 (arterial partial pressure of carbon dioxide), 25.5 mm Hg; SaO2 (arterial oxygen saturation), 82.5%; and PAO2–PaO2 (alveolar–arterial difference in partial pressure of oxygen), 74.7 mm Hg.

 


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Fig. 3A 23-year-old woman with chest pain and dyspnea. CT pulmonary angiography performed with 16-MDCT in sagittal multiplanar reconstruction (A) and axial projection (B) shows endoluminal defects (arrows). Patient had segmental clot receiving pulmonary artery obstruction index of 7.5%. Blood gas values were PaO2 (arterial partial pressure of oxygen), 91.8 mm Hg; PaCO2 (arterial partial pressure of carbon dioxide), 33.8 mm Hg; SaO2 (arterial oxygen saturation), 97%; and PAO2–PaO2 (alveolar–arterial difference in partial pressure of oxygen), 15.95 mm Hg.

 


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Fig. 3B 23-year-old woman with chest pain and dyspnea. CT pulmonary angiography performed with 16-MDCT in sagittal multiplanar reconstruction (A) and axial projection (B) shows endoluminal defects (arrows). Patient had segmental clot receiving pulmonary artery obstruction index of 7.5%. Blood gas values were PaO2 (arterial partial pressure of oxygen), 91.8 mm Hg; PaCO2 (arterial partial pressure of carbon dioxide), 33.8 mm Hg; SaO2 (arterial oxygen saturation), 97%; and PAO2–PaO2 (alveolar–arterial difference in partial pressure of oxygen), 15.95 mm Hg.

 


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Fig. 4 Scatter diagram of pulmonary artery obstruction index versus PaCO2 (arterial partial pressure of carbon dioxide) illustrates sensitivity (78%) and specificity (82%) of PaCO2 = 30 mm Hg (dotted line) for indicating severe pulmonary embolism (pulmonary artery obstruction index > 50%).

 

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