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Carotid Artery Calcification on CT May Independently Predict Stroke Risk

Kiran R. Nandalur1, Erol Baskurt1, Klaus D. Hagspiel1, Michael Finch1, C. Douglas Phillips1, Sirisha R. Bollampally2 and Christopher M. Kramer1

1 Department of Radiology, University of Virginia, PO Box 800170, Charlottesville, VA
2 Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI.


Figure 1
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  		Fig. 1A —Contrast-enhanced MDCT images of heavily calcified cervical carotid arteries in 67-year-old woman. Axial view shows right internal carotid artery just superior to bifurcation.

 

Figure 2
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  		Fig. 1B —Contrast-enhanced MDCT images of heavily calcified cervical carotid arteries in 67-year-old woman. Coronal reconstruction.

 

Figure 3
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  		Fig. 1C —Contrast-enhanced MDCT images of heavily calcified cervical carotid arteries in 67-year-old woman. Axial view shows left internal carotid artery just superior to bifurcation.

 

Figure 4
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  		Fig. 2 —Scatterplot with data points connected by line shows odds ratio for symptoms plotted against calcium scores based on exponential of B coefficient from adjusted multiple logistic regression (0.0079) multiplied by raw calcium score in cubic millimeters. There was considerable increase in odds for occurrence of symptoms with increasing calcium scores.

 

Figure 5
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  		Fig. 3 —Bar graph with SD error bars shows mean vessel scores by degree of stenosis: mild-grade stenosis or normal (0-29%), n = 44; moderate-grade stenosis (30-59%), n = 15; and high-grade stenosis (60%), n = 43. Vessels with high- and moderate-grade stenosis had significantly higher scores than those with mild-grade stenosis or normal vessels (p < 0.005). There was no significant difference between scores of high- and moderate-grade stenotic vessels (p = 0.82). Asterisks indicate p < 0.05.

 

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