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Computer-Assisted Reader Software Versus Expert Reviewers for Polyp Detection on CT Colonography

Stuart A. Taylor1,2, Steve Halligan1,2, David Burling1, Mary E. Roddie3, Lesley Honeyfield4, Justine McQuillan4, Hamdam Amin4 and Jamshid Dehmeshki4

1 Department of Intestinal Imaging, St. Mark's and Northwick Park Hospitals, Watford Rd., Harrow HA1 3UJ, United Kingdom.
2 Present address: Department of Specialist X-ray, University College Hospital, 235 Euston Rd., London NW1 2BU, United Kingdom.
3 Department of Radiology, Charing Cross Hospital, London, United Kingdom.
4 Medicsight PLC, London, United Kingdom.


Figure 1
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  		Fig. 1A —Asymptomatic 68-year-old woman undergoing colorectal cancer screening. Axial CT colonographic image shows method of polyp annotation via a hand-drawn region of interest (in this case, an 11-mm polyp in ascending colon).

 

Figure 2
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  		Fig. 1B —Asymptomatic 68-year-old woman undergoing colorectal cancer screening. Axial CT colonographic image shows method of highlighting polyp candidates used via CAR (computer-assisted reader) software (Medicsight PLC). Potential polyps are ringed as shown.

 

Figure 3
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  		Fig. 2A —Asymptomatic 68-year-old man undergoing colorectal cancer screening. Axial CT colonographic images show 11-mm polyp in ascending colonic polyp (arrow) that was not detected by polyp enhancement filter setting tested. Polyp is submerged in tagged fluid on both supine (A) and prone (B) images.

 

Figure 4
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  		Fig. 2B —Asymptomatic 68-year-old man undergoing colorectal cancer screening. Axial CT colonographic images show 11-mm polyp in ascending colonic polyp (arrow) that was not detected by polyp enhancement filter setting tested. Polyp is submerged in tagged fluid on both supine (A) and prone (B) images.

 

Figure 5
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  		Fig. 3A —Asymptomatic 56-year-old man undergoing colorectal cancer screening. CT colonographic images of sigmoid polyp. Two of three expert reviewers missed polyp (arrow) on this image. Note documented measurement of 6 mm.

 

Figure 6
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  		Fig. 3B —Asymptomatic 56-year-old man undergoing colorectal cancer screening. CT colonographic images of sigmoid polyp. Polyp is correctly highlighted by CAR (computer-assisted reader) software (Medicsight PLC).

 

Figure 7
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  		Fig. 4 —Asymptomatic 65-year-old woman undergoing colorectal cancer screening. Axial CT colonographic image shows false-positive polyp finding highlighted by CAR (computer-assisted reader) software (Medicsight PLC) at interface of air and tagged fluid. False-positive finding is easily dismissed on axial scrolling.

 

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