Technical Feasibility and Biocompatibility of a Newly Designed Separating Stent-Graft in the Normal Canine Aorta
Young-Cheol Weon1,
Sung-Gwon Kang2,
Jin Wook Chung3,
Young Il Kim3,
Jae Hyung Park3 and
Do Yun Lee4
1 Department of Radiology, Samsung Medical Center, Sungkyunkwan University
College of Medicine, Seoul, Korea.
2 Department of Interventional Radiology, Seoul National University College of
Medicine, Seoul National University Bundang Hospital, 300 Gumidong,
Bundang-gu, Seongnam-si, Gyeonggi-do 463-707, Korea.
3 Department of Diagnostic Radiology, Seoul National University Hospital, Seoul
National University College of Medicine, Seoul, Korea.
4 Department of Diagnostic Radiology, Severance Hospital, Yonsei University
College of Medicine, Seoul, Korea.

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Fig. 1A Components of separating stent-graft (34 mm x 10 cm). Outer
graft-stent consists of three parts: proximal stent (A), graft made of
synthetic ultrathin polyester textile fabric (B), and distal stent
(C).
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Fig. 1B Components of separating stent-graft (34 mm x 10 cm). Outer
graft-stent consists of three parts: proximal stent (A), graft made of
synthetic ultrathin polyester textile fabric (B), and distal stent
(C).
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Fig. 1C Components of separating stent-graft (34 mm x 10 cm). Outer
graft-stent consists of three parts: proximal stent (A), graft made of
synthetic ultrathin polyester textile fabric (B), and distal stent
(C).
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Fig. 2 Diagrams show components of separating stent-graft introducing
system: 10-French synthetic resin sheath (A), synthetic resin pusher (B), coil
pusher (C), guidewire-passing tube (D), olive tip (E), loader for inner bare
stent (F), loader pusher (G), and pusher for inner bare stent (H). (Reprinted
with permission from Kang et al.
[16])
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Fig. 3A Case from 12-week follow-up. Three angiograms obtained before
(A), just after (B), and 12 weeks after stent-graft placement
(C) in dog in 12-week follow-up group. Stent is intact without any
deformity or migration in follow-up angiogram. Transparent neointima covers
all stent-grafts. This neointima was very thin (< 1 mm) and regular on
gross (D) and microscopic (E) examination.
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Fig. 3B Case from 12-week follow-up. Three angiograms obtained before
(A), just after (B), and 12 weeks after stent-graft placement
(C) in dog in 12-week follow-up group. Stent is intact without any
deformity or migration in follow-up angiogram. Transparent neointima covers
all stent-grafts. This neointima was very thin (< 1 mm) and regular on
gross (D) and microscopic (E) examination.
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Fig. 3C Case from 12-week follow-up. Three angiograms obtained before
(A), just after (B), and 12 weeks after stent-graft placement
(C) in dog in 12-week follow-up group. Stent is intact without any
deformity or migration in follow-up angiogram. Transparent neointima covers
all stent-grafts. This neointima was very thin (< 1 mm) and regular on
gross (D) and microscopic (E) examination.
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Fig. 3D Case from 12-week follow-up. Three angiograms obtained before
(A), just after (B), and 12 weeks after stent-graft placement
(C) in dog in 12-week follow-up group. Stent is intact without any
deformity or migration in follow-up angiogram. Transparent neointima covers
all stent-grafts. This neointima was very thin (< 1 mm) and regular on
gross (D) and microscopic (E) examination.
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Fig. 3E Case from 12-week follow-up. Three angiograms obtained before
(A), just after (B), and 12 weeks after stent-graft placement
(C) in dog in 12-week follow-up group. Stent is intact without any
deformity or migration in follow-up angiogram. Transparent neointima covers
all stent-grafts. This neointima was very thin (< 1 mm) and regular on
gross (D) and microscopic (E) examination.
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Fig. 4A Case from 4-week follow-up group. Three angiograms obtained before
(A), just after (B), and 4 weeks after stent-graft placement in
dog in 4-week follow-up group (C). Focal narrowing was present at
distal part of stent.
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Fig. 4B Case from 4-week follow-up group. Three angiograms obtained before
(A), just after (B), and 4 weeks after stent-graft placement in
dog in 4-week follow-up group (C). Focal narrowing was present at
distal part of stent.
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Fig. 4C Case from 4-week follow-up group. Three angiograms obtained before
(A), just after (B), and 4 weeks after stent-graft placement in
dog in 4-week follow-up group (C). Focal narrowing was present at
distal part of stent.
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Fig. 4D Case from 4-week follow-up group. On gross examination, dark brown
hematoma was present in this distal portion of stent-graft.
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Fig. 4E Case from 4-week follow-up group. Microscopic examination at site of
focal hematoma shows thin intimal cell layer, subintimal hematoma, and
proliferation of smooth-muscle cells. In other portion, thin regular
neointimal cell layer and smooth-muscle cell layer were observed.
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Copyright © 2006 by the American Roentgen Ray Society.