AJR
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shiraishi, S.
Right arrow Articles by Yamashita, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shiraishi, S.
Right arrow Articles by Yamashita, Y.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Hotlight (NEW!)
Right arrow
What's Hotlight?

Quantitative Analysis and Effect of Attenuation Correction on Lymph Node Staging of Non-Small Cell Lung Cancer on SPECT and CT

Shinya Shiraishi1, Seiji Tomiguchi1, Daisuke Utsunomiya1, Koichi Kawanaka1, Kazuo Awai1, Syoji Morishita1, Tomoko Okuda1, Koichi Yokotsuka2 and Yasuyuki Yamashita1

1 Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto-city, Kumamoto 860-8556, Japan.
2 Nuclear Medicine Department, Hitachi Medical Corporation, Tokyo, Japan.


Figure 1
View larger version (18K):

[in a new window]
  		Fig. 1 —Flow chart shows schema of SPECT and CT image processing. ML-EM = maximum-likelihood expectation maximization, AC = attenuation-corrected, NC = non-attenuation-corrected.

 

Figure 2
View larger version (30K):

[in a new window]
  		Fig. 2 —Receiver operating characteristic curves show areas under curve (Az) for diagnostic indexes. ER = early ratio, DR = delayed ratio, WR = washout ratio, NC = non-attenuation corrected, AC = attenuation corrected.

 

Figure 3
View larger version (25K):

[in a new window]
  		Fig. 3A —51-year-old woman with adenocarcinoma of right middle lobe of lung (arrowheads). CT images depict subcarinal (large arrow) and mediastinal (small arrow) lymph nodes.

 

Figure 4
View larger version (31K):

[in a new window]
  		Fig. 3B —51-year-old woman with adenocarcinoma of right middle lobe of lung (arrowheads). Although attenuation-corrected SPECT images (early phase) reveal multiple high accumulations (arrows), anatomic information is poor.

 

Figure 5
View larger version (32K):

[in a new window]
  		Fig. 3C —51-year-old woman with adenocarcinoma of right middle lobe of lung (arrowheads). On fused SPECT/CT images, accumulations of right hilar and mediastinal lymph nodes (open arrows) may be distinguished from heart and vertebra (dotted arrows). All lymph nodes with thallium-201 accumulation were confirmed at surgical pathology to be metastatic.

 

Figure 6
View larger version (63K):

[in a new window]
  		Fig. 4A —63-year-old man with large cell carcinoma of left lower lobe. Transverse SPECT images show accumulation of thallium-201 in a mediastinal lymph node (arrowheads). On early images without (A) and with (B) attenuation correction, accumulation of thallium-201 in lymph nodes was higher than on delayed images without (C) and with (D) attenuation correction. On early (B) and delayed (D) images with attenuation correction, accumulation in lymph nodes was more clearly depicted than on early (A) and delayed (C) images without attenuation correction.

 

Figure 7
View larger version (69K):

[in a new window]
  		Fig. 4B —63-year-old man with large cell carcinoma of left lower lobe. Transverse SPECT images show accumulation of thallium-201 in a mediastinal lymph node (arrowheads). On early images without (A) and with (B) attenuation correction, accumulation of thallium-201 in lymph nodes was higher than on delayed images without (C) and with (D) attenuation correction. On early (B) and delayed (D) images with attenuation correction, accumulation in lymph nodes was more clearly depicted than on early (A) and delayed (C) images without attenuation correction.

 

Figure 8
View larger version (62K):

[in a new window]
  		Fig. 4C —63-year-old man with large cell carcinoma of left lower lobe. Transverse SPECT images show accumulation of thallium-201 in a mediastinal lymph node (arrowheads). On early images without (A) and with (B) attenuation correction, accumulation of thallium-201 in lymph nodes was higher than on delayed images without (C) and with (D) attenuation correction. On early (B) and delayed (D) images with attenuation correction, accumulation in lymph nodes was more clearly depicted than on early (A) and delayed (C) images without attenuation correction.

 

Figure 9
View larger version (70K):

[in a new window]
  		Fig. 4D —63-year-old man with large cell carcinoma of left lower lobe. Transverse SPECT images show accumulation of thallium-201 in a mediastinal lymph node (arrowheads). On early images without (A) and with (B) attenuation correction, accumulation of thallium-201 in lymph nodes was higher than on delayed images without (C) and with (D) attenuation correction. On early (B) and delayed (D) images with attenuation correction, accumulation in lymph nodes was more clearly depicted than on early (A) and delayed (C) images without attenuation correction.

 

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?



HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2006 by the American Roentgen Ray Society.