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Unintended Thermal Injuries from Radiofrequency Ablation: Protection with 5% Dextrose in Water

Paul F. Laeseke1, Lisa A. Sampson1, Chris L. Brace1, Thomas C. Winter, III1, Jason P. Fine2 and Fred T. Lee, Jr.1

1 Department of Radiology, University of Wisconsin, 600 Highland Ave., Madison, WI 53792-3252.
2 Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53792.


Figure 1
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Fig. 1 —Photograph of circular linoleum spacer placed between diaphragm and liver. Spacer is approximately 6.5 cm in outer diameter, 2.7 cm in inner diameter, and 2.7 mm thick. To prevent liver tissue from contacting diaphragm, 3-0 coated Vicryl sutures (Ethicon) have been placed in 0.5-cm grid pattern over central cavity. Rear view of spacer shows four channels to allow free circulation of fluid (arrow).

 

Figure 2
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Fig. 2 —Bar graph showing mean surface area of thermal lesions created in liver (blue), diaphragm (red), and lung (yellow) for each group. D5 = 5% dextrose in water.

 

Figure 3
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Fig. 3A —Photographs of thermal lesions in liver, diaphragm, and lung. Thermal lesions in liver (left), diaphragm (center), and lung (right) in control subject with no pretreatment. Areas of liver, diaphragm, and lung lesions were 23.1, 12.1, and 10.7 cm2, respectively.

 

Figure 4
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Fig. 3B —Photographs of thermal lesions in liver, diaphragm, and lung. Thermal lesions in liver (left), diaphragm (center), and lung (right) in subject pretreated with normal saline. Areas of liver, diaphragm, and lung lesions were 16.9, 14.3, and 10.8 cm2, respectively.

 

Figure 5
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Fig. 3C —Photographs of thermal lesions in liver, diaphragm, and lung. Thermal lesions in liver (left), diaphragm (center), and lung (right) in subject treated with 5% dextrose in water. Areas of liver, diaphragm, and lung lesions were 10.5, 1.3, and 0.7 cm2, respectively.

 

Figure 6
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Fig. 4 —Photograph of severe diaphragm injury that resulted in perforation (arrow) in control animal.

 

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