AJR
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Brillet, P.-Y.
Right arrow Articles by Vilgrain, V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Brillet, P.-Y.
Right arrow Articles by Vilgrain, V.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Hotlight (NEW!)
Right arrow
What's Hotlight?

Percutaneous Radiofrequency Ablation for Hepatocellular Carcinoma Before Liver Transplantation: A Prospective Study with Histopathologic Comparison

Pierre-Yves Brillet1, Valérie Paradis2, Giuseppe Brancatelli3,4, Anne-Sophie Rangheard3, Yann Consigny5, Aurélie Plessier5, François Durand5, Jacques Belghiti6, Daniele Sommacale6 and Valérie Vilgrain1,7

1 Department of Radiology, APHP-Hôpital Beaujon, 100 Boulevard du General Leclerc, Clichy 92118, France.
2 Department of Pathology, APHP-Hôpital Beaujon, Clichy 92118, France.
3 Department of Radiology, Ospedale Specializzato in Gastroenterologia "Saverio de Bellis" IRCCS, Castellana Grotte (Bari) 70013, Italia.
4 Istituto di Radiologia, Università di Palermo, Via del Vespro 127, 90127 Palermo, Italy.
5 Department of Hepatology, APHP-Hôpital Beaujon, Clichy 92118, France.
6 Department of Digestive Surgery and Transplantation Unit, APHP-Hôpital Beaujon, Clichy 92118, France.
7 INSERM unité 773, CRB3. Faculté Xavier-Bichat, 16 rue Henri Huchart, 75018 Paris, France.


Figure 1
View larger version (16K):

[in a new window]
  		Fig. 1 —Bar graph shows outcomes of 21 patients with hepatocellular carcinoma treated by percutaneous radiofrequency ablation. White bars indicate waiting list; gray bars, transplantation; and black bars, exclusion. Numbers in bars are number of patients.

 

Figure 2
View larger version (153K):

[in a new window]
  		Fig. 2A —63 year-old man (patient 7) waiting for liver transplantation because of hepatocellular carcinoma, in whom complete necrosis of tumor was achieved through percutaneous radiofrequency ablation. Arterial-phase contrast-enhanced transverse helical CT scan before treatment shows 25-mm hyperattenuating hepatocellular carcinoma (white arrow) in right posterior hepatic segment.

 

Figure 3
View larger version (136K):

[in a new window]
  		Fig. 2B —63 year-old man (patient 7) waiting for liver transplantation because of hepatocellular carcinoma, in whom complete necrosis of tumor was achieved through percutaneous radiofrequency ablation. Arterial-phase contrast-enhanced transverse helical CT scan during follow-up (4 months after percutaneous radiofrequency ablation and 8 days before liver transplantation) shows arterioportal shunting (white star) and absence of arterial enhancement (white arrow) within tumor because of complete necrosis.

 

Figure 4
View larger version (140K):

[in a new window]
  		Fig. 2C —63 year-old man (patient 7) waiting for liver transplantation because of hepatocellular carcinoma, in whom complete necrosis of tumor was achieved through percutaneous radiofrequency ablation. Pathologic examination of explanted liver confirmed complete necrosis of tumor but showed multiple satellite nodules (black arrows) and fibrous peritumoral capsule (white arrow).

 

Figure 5
View larger version (122K):

[in a new window]
  		Fig. 3A —60 year-old man (patient 14) waiting for liver transplantation because of hepatocellular carcinoma, in whom incomplete necrosis of tumor was achieved through percutaneous radiofrequency ablation. Arterial-phase contrast-enhanced transverse helical CT scan shows 5-cm hypoattenuating hepatocellular carcinoma. Enhancement was seen only in small, peripheral portion of tumor (white arrow).

 

Figure 6
View larger version (130K):

[in a new window]
  		Fig. 3B —60 year-old man (patient 14) waiting for liver transplantation because of hepatocellular carcinoma, in whom incomplete necrosis of tumor was achieved through percutaneous radiofrequency ablation. Gadolinium-enhanced T1-weighted fat-suppressed gradient-echo MR image (TR/TE, 216/5.1; flip angle, 80°) obtained during portal venous phase (B) and fat-suppressed T2-weighted fast spin-echo MR image (1,600/70) (C) 2 months after percutaneous radiofrequency ablation and 4 days before liver transplantation show residual tumor (white arrow).

 

Figure 7
View larger version (120K):

[in a new window]
  		Fig. 3C —60 year-old man (patient 14) waiting for liver transplantation because of hepatocellular carcinoma, in whom incomplete necrosis of tumor was achieved through percutaneous radiofrequency ablation. Gadolinium-enhanced T1-weighted fat-suppressed gradient-echo MR image (TR/TE, 216/5.1; flip angle, 80°) obtained during portal venous phase (B) and fat-suppressed T2-weighted fast spin-echo MR image (1,600/70) (C) 2 months after percutaneous radiofrequency ablation and 4 days before liver transplantation show residual tumor (white arrow).

 

Figure 8
View larger version (158K):

[in a new window]
  		Fig. 3D —60 year-old man (patient 14) waiting for liver transplantation because of hepatocellular carcinoma, in whom incomplete necrosis of tumor was achieved through percutaneous radiofrequency ablation. Pathologic examination of explant confirmed tumor recurrence (black arrow). This patient had microvascular invasion.

 

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?



HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2006 by the American Roentgen Ray Society.