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CT Features of Hepatic Venoocclusive Disease and Hepatic Graft-Versus-Host Disease in Patients After Hematopoietic Stem Cell Transplantation

Sukru Mehmet Erturk1, Koenraad J. Mortelé1, Christoph A. Binkert2, Jonathan N. Glickman3, Maria-Raquel Oliva1, Pablo R. Ros1 and Stuart G. Silverman1

1 Division of Abdominal Imaging and Intervention, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Radiology Ste., c/o One Brigham Circle, 1620 Tremont St., Boston, MA 02120.
2 Division of Angiography and Interventional Radiology, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
3 Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.


Figure 1
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  		Fig. 1A —28-year-old woman with venoocclusive disease after hematopoietic stem cell transplantation. Axial CT images show ascites, narrowed right hepatic vein (arrow, A), and periportal edema (arrow, B).

 

Figure 2
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  		Fig. 1B —28-year-old woman with venoocclusive disease after hematopoietic stem cell transplantation. Axial CT images show ascites, narrowed right hepatic vein (arrow, A), and periportal edema (arrow, B).

 

Figure 3
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  		Fig. 1C —28-year-old woman with venoocclusive disease after hematopoietic stem cell transplantation. Pathologic evaluation yielded marked congestion consistent with venoocclusive disease.

 

Figure 4
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  		Fig. 2A —62-year-old man with graft-versus-host disease after hematopoietic stem cell transplantation. Axial CT images show small bowel wall thickening affecting ileal loops (arrow, A), healthy right hepatic vein (arrow, B), and no evidence of periportal edema (arrow, C).

 

Figure 5
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  		Fig. 2B —62-year-old man with graft-versus-host disease after hematopoietic stem cell transplantation. Axial CT images show small bowel wall thickening affecting ileal loops (arrow, A), healthy right hepatic vein (arrow, B), and no evidence of periportal edema (arrow, C).

 

Figure 6
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  		Fig. 2C —62-year-old man with graft-versus-host disease after hematopoietic stem cell transplantation. Axial CT images show small bowel wall thickening affecting ileal loops (arrow, A), healthy right hepatic vein (arrow, B), and no evidence of periportal edema (arrow, C).

 

Figure 7
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  		Fig. 2D —62-year-old man with graft-versus-host disease after hematopoietic stem cell transplantation. Pathologic evaluation shows apoptosis and degenerative changes consistent with graft-versus-host disease.

 

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