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Quantitative Assessment of Tissue Perfusion Using MDCT: Comparison of Colorectal Cancer and Skeletal Muscle Measurement Reproducibility

Vicky Goh1, Steve Halligan2,3, Jo-Ann Hugill2 and Clive I. Bartram2

1 Paul Strickland Scanner Centre, Mt. Vernon Hospital, Northwood, United Kingdom.
2 Intestinal Imaging Centre, St. Mark's Hospital, Middlesex, HA1 3UJ, United Kingdom.
3 Present address: Specialist Radiology, University College Hospital, 235 Euston Road, London, NW1 2BU, United Kingdom.


Figure 1
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  		Fig. 1A —84-year-old woman. Axial image shows T3 rectal tumor. Region of interest (ROI) has been placed within left external iliac artery to define arterial input and drawn around tumor to define tissue ROI.

 

Figure 2
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  		Fig. 1B —84-year-old woman. Corresponding graph of tissue attenuation (H, y axis) plotted against time (seconds, x axis) shows arterial and tumor attenuation change with time; peak arterial enhancement is higher than tumor enhancement (420 H vs 108 H).

 

Figure 3
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  		Fig. 1C —84-year-old woman. Blood volume (C), blood flow (D), mean transit time (E), and permeability (F) maps corresponding to A.

 

Figure 4
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  		Fig. 1D —84-year-old woman. Blood volume (C), blood flow (D), mean transit time (E), and permeability (F) maps corresponding to A.

 

Figure 5
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  		Fig. 1E —84-year-old woman. Blood volume (C), blood flow (D), mean transit time (E), and permeability (F) maps corresponding to A.

 

Figure 6
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  		Fig. 1F —84-year-old woman. Blood volume (C), blood flow (D), mean transit time (E), and permeability (F) maps corresponding to A.

 

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