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Fluoroscopic Contrast-Enhanced MR Angiography with a Magnetization-Prepared Steady-State Free Precession Technique in Peripheral Arterial Occlusive Disease

Rolf W. Huegli1, Markus Aschwanden2, Klaus Scheffler3 and Deniz Bilecen1

1 Department of Radiology, University Hospital of Basel, Petersgraben 4, 4031 Basel, Switzerland.
2 Department of Angiology, University Hospital of Basel, 4031 Basel, Switzerland.
3 Medical Physics, Department of Radiology, University Hospital of Basel, 4031 Basel, Switzerland.


Figure 1
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Fig. 1A Diagram illustrates technique used for optimized background suppression, and graph shows acceptable contrast-to-noise ratios (CNRs) were obtained. Schematic diagram illustrates magnetization prepared steady-state free precession (SSFP) technique for intraarterial near-real-time contrast-enhanced MRI. To gain sufficient background suppression and enhanced T1 weighting, nonselective excitation pulse of 130° and frequency-selective fat-saturation pulse were inserted between consecutive 2D projection acquisitions.

 

Figure 2
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Fig. 1B Diagram illustrates technique used for optimized background suppression, and graph shows acceptable contrast-to-noise ratios (CNRs) were obtained. Sequential CNR curve progression at thigh and calf levels. First two acquisitions are discarded and following three images are averaged to create mask image (nonselective excitation). Slope of CNR curve is steeper and reaches earlier plateau at thigh level ({blacktriangleup}) than calf level (•). Because contrast medium was injected in both cases at proximal femoral level, CNR curve is observably higher in femoropopliteal axis.

 

Figure 3
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Fig. 2A Complex subtracted intraarterial (IA) near-real-time contrast-enhanced MRI of 69-year-old man with peripheral arterial occlusive disease. Acquisition time was 700 milliseconds per frame. Superficial femoral artery and proximal parts of popliteal artery are clearly delineated. Only mild venous filling and parenchymal flush can be observed in images h, i, and j.

 

Figure 4
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Fig. 2B Complex subtracted intraarterial (IA) near-real-time contrast-enhanced MRI of 69-year-old man with peripheral arterial occlusive disease. Acquisition time was 700 milliseconds per frame. Images a-f show two-vessel runoff over peroneal and posterior tibial arteries. In images g-j, mild venous filling and parenchymal flush can be seen.

 

Figure 5
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Fig. 2C Complex subtracted intraarterial (IA) near-real-time contrast-enhanced MRI of 69-year-old man with peripheral arterial occlusive disease. Acquisition time was 700 milliseconds per frame. Calculated MR road map image (C) compared with IA digital subtraction angiography (DSA) image (D). Clear delineation of two-vessel runoff via posterior tibial and fibular arteries. Stenoses are overestimated on MR image compared with IA DSA.

 

Figure 6
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Fig. 2D Complex subtracted intraarterial (IA) near-real-time contrast-enhanced MRI of 69-year-old man with peripheral arterial occlusive disease. Acquisition time was 700 milliseconds per frame. Calculated MR road map image (C) compared with IA digital subtraction angiography (DSA) image (D). Clear delineation of two-vessel runoff via posterior tibial and fibular arteries. Stenoses are overestimated on MR image compared with IA DSA.

 

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