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How Predictive Is Breast Arterial Calcification of Cardiovascular Disease and Risk Factors When Found at Screening Mammography?

Masako Kataoka1, Ruth Warren2, Robert Luben3, Joanna Camus3, Erika Denton4, Elvis Sala1, Nicholas Day3 and Kay-Tee Khaw5

1 Department of Radiology, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.
2 Cambridge Breast Unit, Addenbrooke's Hospital, University of Cambridge, Hills Rd., Cambridge, CB2 2QQ, United Kingdom.
3 Strangeways Research Laboratory, Institute of Public Health, University of Cambridge, Cambridge, United Kingdom.
4 Department of Radiology, Norfolk and Norwich University Hospital, Norwich, United Kingdom.
5 Clinical Gerontology Unit, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.


Figure 1
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Fig. 1 Model for breast arterial calcification (BAC) and cardiovascular disease and risk factors. Hypothesis 1 = BAC is associated with cardiovascular disease. Hypothesis 2 = BAC is associated with established cardiovascular risk factors. BMI = body mass index, LDL = low-density lipoprotein, DM = diabetes mellitus, HbA1c = glycosylated hemoglobin.

 

Figure 2
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Fig. 2 63-year-old woman with typical breast arterial calcification found in mammogram. Parallel calcific line, described as railroad track configuration, is distinctive as benign finding.

 

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