Variability of Repeated Coronary Artery Calcium Measurements on Low-Dose ECG-Gated 16-MDCT
Jun Horiguchi1,
Hideya Yamamoto2,
Nobuhiko Hirai1,
Yuji Akiyama1,
Chikako Fujioka1,
Kazushi Marukawa3,
Hiroshi Fukuda1 and
Katsuhide Ito3
1 Department of Clinical Radiology, Hiroshima University Hospital, 1-2-3,
Kasumi-cho, Minami-ku, Hiroshima 734-8551, Japan.
2 Department of Molecular and Internal Medicine, Division of Clinical Medical
Science, Programs for Applied Biomedicine, Graduate School of Biomedical
Sciences, Hiroshima University, Hiroshima, Japan.
3 Department of Radiology, Division of Medical Intelligence and Informatics,
Programs for Applied Biomedicine, Graduate School of Biomedical Sciences,
Hiroshima University, Hiroshima, Japan.
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Fig. 1A —Placement of region of interest (ROI, circles) in
64-year-old man complaining of chest pain (heart rate, 68 beats per minute;
body weight, 62 kg). Transaxial helical CT images of heart obtained using
100-mA (A), first 60-mA (B), and second 60-mA (C)
protocols. Mean and SD CT attenuation values (Hounsfield units) in ROIs set in
aorta at level of left coronary artery were 49 ± 14, 47 ± 19,
and 45 ± 19 H, respectively. Value means + 2 x SD were 76, 85,
and 83 H, respectively. Calcium in left main coronary and anterior descending
arteries is well shown on all helical CT scans.
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Fig. 1B —Placement of region of interest (ROI, circles) in
64-year-old man complaining of chest pain (heart rate, 68 beats per minute;
body weight, 62 kg). Transaxial helical CT images of heart obtained using
100-mA (A), first 60-mA (B), and second 60-mA (C)
protocols. Mean and SD CT attenuation values (Hounsfield units) in ROIs set in
aorta at level of left coronary artery were 49 ± 14, 47 ± 19,
and 45 ± 19 H, respectively. Value means + 2 x SD were 76, 85,
and 83 H, respectively. Calcium in left main coronary and anterior descending
arteries is well shown on all helical CT scans.
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Fig. 1C —Placement of region of interest (ROI, circles) in
64-year-old man complaining of chest pain (heart rate, 68 beats per minute;
body weight, 62 kg). Transaxial helical CT images of heart obtained using
100-mA (A), first 60-mA (B), and second 60-mA (C)
protocols. Mean and SD CT attenuation values (Hounsfield units) in ROIs set in
aorta at level of left coronary artery were 49 ± 14, 47 ± 19,
and 45 ± 19 H, respectively. Value means + 2 x SD were 76, 85,
and 83 H, respectively. Calcium in left main coronary and anterior descending
arteries is well shown on all helical CT scans.
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Fig. 2 —Graph shows that log10 transformed scores
(Agatston scores + 1) of 100-mA scans versus first low-dose scans are highly
correlated (r = 0.998). In this logarithm calcium scale, 0,  1,
2, 2.6, and > 2.6 ranges almost correspond to normal, minimal,
mild, moderate, and high-risk categories, respectively.
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Fig. 3 —Graph shows that log10 transformed scores
(Agatston scores + 1) of 100-mA scans and second low-dose scans are highly
correlated (r = 0.998). In this logarithm calcium scale, 0, 1,
2, 2.6, and > 2.6 ranges almost correspond to normal, minimal,
mild, moderate, and high-risk categories, respectively.
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View larger version (13K):
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Fig. 4 —Graph shows that log10 transformed scores
(Agatston scores + 1) of first low-dose scans and second low-dose scans are
highly correlated (r = 0.998). In this logarithm calcium scale, 0,
1, 2, 2.6, and > 2.6 ranges almost correspond to normal,
minimal, mild, moderate, and high-risk categories, respectively.
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Copyright © 2006 by the American Roentgen Ray Society.
