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High-Spatial-Resolution MRI of Non-Masslike Breast Lesions: Interpretation Model Based on BI-RADS MRI Descriptors

Mitsuhiro Tozaki1,2 and Kunihiko Fukuda2

1 Present address: Division of Diagnostic Imaging, Breast Center, Kameda Medical Center, 929 Higashi-cho, Kamogawa, Chiba, Japan 296-8602.
2 Department of Radiology, The Jikei University School of Medicine, 3-25-8 Nishi-Shimbashi, Minato-ku, Tokyo 105-8461, Japan.


Figure 1
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Fig. 1 Interpretation method of non-masslike enhancement. First, distribution patterns were classified into three categories (single quadrant/solitary lesion, single quadrant/grouped lesion, and multiquadrant lesion). Second, presence of ductal pattern was assessed in enhancing lesions. Third, internal enhancement was evaluated. Fourth, in addition to BI-RADS MRI descriptors, presence of clustered ring enhancement was also assessed in heterogeneous enhancing lesions (positive or negative).

 

Figure 2
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Fig. 2 Interpretation model of non-masslike enhancement based on BI-RADS MRI descriptors. Benign terminal nodes are shaded. Positive predictive value was 94% (17/18).

 

Figure 3
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Fig. 3 51-year-old woman who presented with bloody nipple discharge of right breast. Coronal first contrast-enhanced T1-weighted MR image shows linear-ductal enhancement in upper outer quadrant (arrows). Craniocaudal and transverse lines are drawn crossing over nipple. Note clumped internal architecture. Histologic evaluation of lumpectomy specimen revealed atypical ductal hyperplasia.

 

Figure 4
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Fig. 4A 47-year-old woman with microcalcifications on mammography. Coronal first contrast-enhanced T1-weighted MR image shows focal enhancement in upper outer quadrant of right breast (arrows).

 

Figure 5
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Fig. 4B 47-year-old woman with microcalcifications on mammography. Sagittal multiplanar reconstruction of first contrast-enhanced T1-weighted MR image shows branching-ductal pattern with homogeneous internal enhancement (arrows).

 

Figure 6
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Fig. 4C 47-year-old woman with microcalcifications on mammography. Histologic evaluation of lumpectomy specimen revealed ductal carcinoma in situ (DCIS). Branching ductal pattern corresponded to DCIS (arrows) with surrounding atrophic tissue.

 

Figure 7
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Fig. 5A 53-year-old woman with palpable nodule of right breast. No abnormalities were seen on mammogram. Coronal first contrast-enhanced T1-weighted MR image shows regional enhancement in lower region of right breast (arrows).

 

Figure 8
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Fig. 5B 53-year-old woman with palpable nodule of right breast. No abnormalities were seen on mammogram. Transverse multiplanar reconstruction of first contrast-enhanced T1-weighted MR image shows nonbranching pattern with clumped internal architecture (arrows).

 

Figure 9
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Fig. 5C 53-year-old woman with palpable nodule of right breast. No abnormalities were seen on mammogram. Histologic evaluation of mastectomy specimen revealed ductal carcinoma in situ (DCIS). Clumped internal architecture corresponded to clusters of multiple ducts enclosed with fibrous stroma (arrows).

 

Figure 10
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Fig. 6A 54-year-old woman with palpable nodule of left breast. Coronal first contrast-enhanced T1-weighted MR image shows segmental enhancement in lower outer quadrant of left breast (arrows).

 

Figure 11
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Fig. 6B 54-year-old woman with palpable nodule of left breast. Transverse third contrast-enhanced T1-weighted MR image at 4 minutes shows nonbranching, heterogeneous enhancement (arrows). Note clustered ring enhancement. Histologic evaluation of mastectomy specimen revealed ductal carcinoma in situ (DCIS).

 

Figure 12
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Fig. 7A 39-year-old woman with palpable nodule of right breast. No abnormalities were seen on mammogram. Transverse multiplanar reconstruction of first contrast-enhanced T1-weighted MR image shows nonbranching, heterogeneous enhancement (arrows). Note clustered ring enhancement.

 

Figure 13
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Fig. 7B 39-year-old woman with palpable nodule of right breast. No abnormalities were seen on mammogram. Histologic evaluation of mastectomy specimen revealed ductal carcinoma in situ (DCIS). Clustered ring enhancement corresponded to crowded and dilated ducts (arrows).

 

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