Unusual Malignant Tumors of the Gallbladder
Min-Jeong Kim1,
Kyoung Won Kim2,
Hyo-Cheol Kim3,
So Yeon Kim2,
Seong Ho Park2,
Ah Young Kim2,
Hyun Kwon Ha2,
Jae Ho Byun2,
Hyung Jin Won2,
Yong Moon Shin2,
Pyo Nyun Kim2 and
Moon-Gyu Lee2
1 Department of Radiology, Hallym University Sacred Heart Hospital, Anyang,
Korea.
2 Department of Radiology, Asan Medical Center, University of Ulsan College of
Medicine, 388-1, Pungnap-2 dong, Songpa-ku, Seoul, Korea 138-736.
3 Department of Radiology, Seoul National University Hospital, Seoul National
University College of Medicine, Seoul, Korea.

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Fig. 1A 71-year-old woman with papillary adenocarcinoma of
gallbladder. Oblique coronal sonogram shows intraluminal polypoid echogenic
masses (arrows) within distended gallbladder.
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Fig. 1B 71-year-old woman with papillary adenocarcinoma of
gallbladder. Contrast-enhanced CT scan clearly depicts polypoid masses
(arrows) with mild enhancement filling neck and body of
gallbladder.
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Fig. 1C 71-year-old woman with papillary adenocarcinoma of
gallbladder. Photograph of gross pathologic specimen shows intraluminal
papillary growing mass in gallbladder.
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Fig. 2A 64-year-old woman with mucinous adenocarcinoma of
gallbladder. Unenhanced CT scan reveals several punctate calcifications
(arrows) and suspicious localized wall thickening in body of
gallbladder.
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Fig. 2B 64-year-old woman with mucinous adenocarcinoma of
gallbladder. On contrast-enhanced CT, mass is clearly visualized as localized
wall thickening with enhancement and some multilocular lesion with rimlike
enhancement (arrow). There also is direct invasion into segment IV of
liver (arrowhead) and metastatic lymphadenopathy (curved
arrow) along bilateral paraaortic area.
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Fig. 3A 43-year-old woman with signet ring cell carcinoma of
gallbladder. Sonogram shows targetlike wall thickening (arrow) of
fundus of gallbladder.
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Fig. 3B 43-year-old woman with signet ring cell carcinoma of
gallbladder. CT scan reveals targetlike wall thickening with enhancement
(arrow) of fundus of gallbladder. There also is noted massive
necrotic lymphadenopathy (arrowheads) along porta hepatis,
hepatoduodenal ligament, and porta cava space.
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Fig. 4A 51-year-old woman with adenosquamous cell carcinoma. On
contrast-enhanced CT scan, huge heterogeneous enhancing mass replaces
gallbladder fossa and directly invades adjacent liver. Mass is composed of
endoluminal (arrow) and exophytic (E) mass with interrupted mucosal
lining.
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Fig. 4B 51-year-old woman with adenosquamous cell carcinoma. On axial
T2-weighted MR image (TR/TE, 4/134), endoluminal mass (arrow) shows
low signal intensity, and exophytic mass (E) shows slightly high signal
intensity.
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Fig. 4C 51-year-old woman with adenosquamous cell carcinoma. Axial
T1-weighted image (TR/TE, 149/4) shows two components, which are endoluminal
polypoid mass with high signal intensity (arrow) and huge exophytic
mass with low signal intensity (E).
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Fig. 4D 51-year-old woman with adenosquamous cell carcinoma. On
gadolinium-enhanced coronal MR image, huge mass with peripheral rim
enhancement (arrows) replaces gallbladder fossa and invades adjacent
liver.
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Fig. 5 64-year-old man with squamous cell carcinoma.
Contrast-enhanced CT scan shows huge mass replacing gallbladder fossa (G) and
direct invasion of adjacent liver (L). No lymphadenopathy is noted.
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Fig. 6A 77-year-old woman with sarcomatoid carcinoma. Sonogram shows
heterogeneous echogenic mass (M) filling gallbladder.
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Fig. 6B 77-year-old woman with sarcomatoid carcinoma.
Contrast-enhanced CT scan shows mild wall thickening of fundus and poorly
enhanced endoluminal mass (M).
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Fig. 6C 77-year-old woman with sarcomatoid carcinoma. Photograph of
gross pathologic specimen shows endoluminal mass in gallbladder with extensive
necrosis (N) and peripheral viable tumor (arrow).
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Fig. 7A 48-year-old woman with small cell carcinoma of gallbladder.
Contrast-enhanced CT scan shows heterogeneous enhancing mass (M) in
gallbladder fossa and adjacent gallbladder wall thickening with enhancement
(arrowhead). There are also noted multiple enlarged lymph nodes at
porta hepatis and along common hepatic artery.
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Fig. 7B 48-year-old woman with small cell carcinoma of gallbladder.
CT scans also reveal enlarged lymph nodes (L) and omental mass (O),
respectively.
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Fig. 7C 48-year-old woman with small cell carcinoma of gallbladder.
CT scans also reveal enlarged lymph nodes (L) and omental mass (O),
respectively.
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Fig. 8A 70-year-old woman with malignant fibrous histiocytoma. Axial
T2-weighted MR image (TR/TE, 4/134) shows huge mass (arrows) in
gallbladder fossa with peripheral high signal intensity and central bright
signal intensity.
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Fig. 8B 70-year-old woman with malignant fibrous histiocytoma. On
gadolinium-enhanced axial MR image, huge mass with peripheral rim enhancement
(arrows) replaces gallbladder fossa.
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Fig. 9A 45-year-old man with Burkitt's lymphoma. Contrast-enhanced CT
scan shows small polypoid mass in gallbladder (arrow).
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Fig. 9B 45-year-old man with Burkitt's lymphoma. Photograph of gross
pathologic specimen shows polypoid mass in gallbladder.
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Fig. 10 67-year-old woman with lymphoma of gallbladder.
Contrast-enhanced CT scan shows markedly diffuse wall thickening of
gallbladder with homogeneous low density (arrows).
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Fig. 11 53-year-old woman with metastatic melanoma of gallbladder.
Contrast-enhanced CT scan shows intraluminal polypoid mass with wall
enhancement (arrow) in gallbladder.
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Fig. 12 62-year-old man with metastatic hepatocellular carcinoma of
gallbladder. Contrast-enhanced CT scan shows polypoid enhancing mass
(arrow) with adjacent wall thickening of gallbladder. There is also
noted hepatocellular carcinoma (arrowhead) containing iodized oil in
liver.
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Copyright © 2006 by the American Roentgen Ray Society.