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PET/CT Characterization of Fibroosseous Defects in Children: 18F-FDG Uptake Can Mimic Metastatic Disease

Geoffrey S. Goodin1,2, Barry L. Shulkin1, Robert A. Kaufman1,2,3 and M. Beth McCarville1,2

1 Division of Diagnostic Imaging, Department of Radiological Sciences, MS 210, St. Jude Children's Research Hospital, 332 N Lauderdale St., Memphis, TN 38105-2794.
2 Department of Radiology, University of Tennessee Health Science Center, Memphis, TN 38163.
3 Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163.


Figure 1
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  		Fig. 1A —6-year-old girl with 2.1-cm nonossifying fibroma of right proximal tibial diametaphysis. Axial PET image shows mild 18F-FDG uptake at location of nonossifying fibroma (arrow).

 

Figure 2
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  		Fig. 1B —6-year-old girl with 2.1-cm nonossifying fibroma of right proximal tibial diametaphysis. Corresponding axial CT image shows nonossifying fibroma (arrow).

 

Figure 3
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  		Fig. 2A —13-year-old boy with 3.2-cm nonossifying fibroma of left distal femoral diaphysis. Axial PET image shows moderate 18F-FDG uptake at location of nonossifying fibroma (arrow).

 

Figure 4
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  		Fig. 2B —13-year-old boy with 3.2-cm nonossifying fibroma of left distal femoral diaphysis. Corresponding axial CT image shows nonossifying fibroma (arrow).

 

Figure 5
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  		Fig. 2C —13-year-old boy with 3.2-cm nonossifying fibroma of left distal femoral diaphysis. Anterior (C) and posterior (D) images from technetium-99m methylene diphosphonate bone scintigraphy, which was performed 1 week before PET/CT, show no activity at location of nonossifying fibroma.

 

Figure 6
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  		Fig. 2D —13-year-old boy with 3.2-cm nonossifying fibroma of left distal femoral diaphysis. Anterior (C) and posterior (D) images from technetium-99m methylene diphosphonate bone scintigraphy, which was performed 1 week before PET/CT, show no activity at location of nonossifying fibroma.

 

Figure 7
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  		Fig. 3A —14-year-old boy with 2.9-cm nonossifying fibroma in left femoral metaphysis. Axial PET image shows intense 18F-FDG uptake at location of nonossifying fibroma (arrow).

 

Figure 8
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  		Fig. 4B —14-year-old boy with 2.9-cm nonossifying fibroma in left femoral metaphysis. Corresponding axial CT scan shows nonossifying fibroma (arrow).

 

Figure 9
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  		Fig. 5A —8-year-old boy with 1-cm cortical desmoid located at posteromedial surface of distal femur. Axial PET image shows moderate 18F-FDG uptake at location of cortical desmoid (arrow).

 

Figure 10
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  		Fig. 5B —8-year-old boy with 1-cm cortical desmoid located at posteromedial surface of distal femur. Corresponding axial CT scan of cortical desmoid (arrow).

 

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