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Lobular Neoplasia at 11-Gauge Vacuum-Assisted Stereotactic Biopsy: Correlation with Surgical Excisional Biopsy and Mammographic Follow-Up

Mary C. Mahoney1, Toni M. Robinson-Smith2 and Elizabeth A. Shaughnessy3

1 Department of Radiology, University of Cincinnati, 234 Goodman St., M.L. 772, Cincinnati, OH 45267.
2 Department of Pathology, University of Cincinnati, Cincinnati, OH.
3 Department of Surgery, University of Cincinnati, Cincinnati, OH.


Figure 1
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  		Fig. 1 —59-year-old woman with classic form of lobular carcinoma in situ who underwent stereotactic vacuum-assisted biopsy. Pleomorphic calcifications are identified on magnification mammogram image of right breast.

 

Figure 2
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  		Fig. 2A —53-year-old woman with classic form of lobular carcinoma in situ who underwent stereotactic vacuum-assisted biopsy. Note expansion of lobular unit by uniform cells. Arrows mark calcifications, which were also identified mammographically.

 

Figure 3
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  		Fig. 2B —53-year-old woman with classic form of lobular carcinoma in situ who underwent stereotactic vacuum-assisted biopsy. Note uniformity of proliferating lobular cells at higher magnification.

 

Figure 4
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  		Fig. 3 —59-year-old woman with pleomorphic form of lobular carcinoma in situ who underwent stereotactic vacuum-assisted biopsy. Note lack of uniformity and atypical changes within proliferating lobular cells.

 

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