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Therapeutic Effect and Outcome Predictors of Sciatica Treated Using Transforaminal Epidural Steroid Injection

Joon Woo Lee1, Sung Hyun Kim1, In Sook Lee1, Jung-Ah Choi1, Ja-Young Choi2, Sung Hwan Hong2 and Heung Sik Kang1

1 Department of Radiology, Seoul National University, Bundang Hospital, 300 Gumi-dong, Bundang-gu, Seong Nam, Gyeongi-Do 463-707, South Korea.
2 Department of Radiology and Institute of Radiation Medicine, Seoul National University Hospital, Chongno-gu, South Korea.


Figure 1
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Fig. 1A 67-year-old man with sciatica. Posteroanterior (A) and lateral (B) spot radiographs obtained during intraepineural injection of transforaminal epidural steroid. Patient was placed in prone position, and needle tip was inserted to left S1 nerve root. Contrast material is well demarcated from outer border, a feathery appearance is apparent in central region, and width of area of opacification is uniform.

 

Figure 2
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Fig. 1B 67-year-old man with sciatica. Posteroanterior (A) and lateral (B) spot radiographs obtained during intraepineural injection of transforaminal epidural steroid. Patient was placed in prone position, and needle tip was inserted to left S1 nerve root. Contrast material is well demarcated from outer border, a feathery appearance is apparent in central region, and width of area of opacification is uniform.

 

Figure 3
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Fig. 2A 59-year-old man with sciatica. Posteroanterior (A) and lateral (B) spot radiographs obtained during extraepineural injection of transforaminal epidural steroid. Patient was in prone position, and needle tip was inserted to left L5 nerve root. Sharp interface is present between nerve root and contrast material, which is well demarcated from outer border. In this case, width of area of opacification is not uniform.

 

Figure 4
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Fig. 2B 59-year-old man with sciatica. Posteroanterior (A) and lateral (B) spot radiographs obtained during extraepineural injection of transforaminal epidural steroid. Patient was in prone position, and needle tip was inserted to left L5 nerve root. Sharp interface is present between nerve root and contrast material, which is well demarcated from outer border. In this case, width of area of opacification is not uniform.

 

Figure 5
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Fig. 3 Graph illustrates effectiveness of intraepineural injection (black bars) and extraepineural injection (white bars) of transforaminal epidural steroid for treatment of sciatica. Extraepineural injections were significantly associated with a better outcome (p < 0.05).

 

Figure 6
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Fig. 4 Graph illustrates effectiveness of transforaminal epidural steroid for treatment of sciatica in patients with saddle-type (white bars) and non-saddle type (black bars) contrast distribution pattern. Number of patients with saddle-type distribution pattern was much greater than with non-saddle type, and saddle-type pattern was associated with a better outcome; however, this difference in outcome was not statistically significant.

 

Figure 7
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Fig. 5 Graph illustrates relation between cause of sciatica and effectiveness of transforaminal epidural steroid for treatment of sciatica. No significant difference in effectiveness was found for patients with sciatica caused by herniated intervertebral disks (black bars) and those with sciatica resulting from spinal stenosis (white bars).

 

Figure 8
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Fig. 6 Graph illustrates effects of patient age on effectiveness of transforaminal epidural steroid for treatment of sciatica. Transforaminal epidural steroid was most effective in 50- to 59-year-old patients (light gray bars) and least effective in those 70 years old or older (white bars). No patient was younger than 29 years. Black bars = 30- to 39-year-old age group, dark gray bars = 40- to 49-year-old age group, and striped bars = 60- to 69-year-old age group.

 

Figure 9
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Fig. 7 Graph illustrates effect of patient sex on effectiveness of transforaminal epidural steroid for treatment of sciatica. No difference was evident. Black bars = men, white bars = women.

 

Figure 10
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Fig. 8 Graph illustrates relation between duration of sciatica and effectiveness of transforaminal epidural steroid for treatment of sciatica. Treatment was more effective in patients with sciatica of < 6 months' duration (acute or subacute, black bars) than in those with sciatica of > 6 months' duration (chronic, white bars), but this difference lacked statistical significance.

 

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