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99mTc-MAG3 Renography: Normal Values for MAG3 Clearance and Curve Parameters, Excretory Parameters, and Residual Urine Volume

Fabio P. Esteves1, Andrew Taylor1, Amita Manatunga2, Russell D. Folks1, Meghna Krishnan1 and Ernest V. Garcia1

1 Department of Radiology, Division of Nuclear Medicine, Emory University Hospital, 1364 Clifton Rd. NE, Atlanta, GA 30322.
2 Department of Biostatistics, Emory University School of Medicine, Atlanta, GA.


Figure 1
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Fig. 1 Standard display of QuantEM 2.0 review screen shows demographic data, dose injected, dose counted on camera, percentage of dose infiltrated, MAG3 (mercaptoacetyltriglycine) clearance, and expected MAG3 clearance, followed by percentage of uptake, Tmax (time to maximum counts), T1/2 (time to half-peak counts), and 20 min/max ratio (ratio of renal counts at 19-20 minutes to maximum counts) for whole-kidney region of interest (ROI). Voided volume and postvoid residual volume are also displayed. Urine flow rate was not measured. Upper central panel shows 2-second images as initial bolus reaches kidney. Upper right panel shows injection site; just beneath is a frame for viewing dynamic cine images, and pre- and postvoiding bladder images. Central panel shows 12 2-minute images followed by postvoid image of kidneys with patient lying on camera in same position as initial images. Lower left panel shows whole-kidney ROIs and whole-kidney renogram curves; lower right panel shows cortical ROIs and cortical renogram curves. (QuantEM is software that was developed at Emory University and is licensed by Emory University to GE Healthcare.)

 

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Fig. 2 Expanded review display shows patient values for MAG3 (mercaptoacetyltriglycine) clearance, residual urine volume, percentage of relative uptake, and Tmax (time to maximum counts), 20 min/max (ratio of renal counts at 19-20 minutes to maximum counts), T1/2 (time to half-peak counts), and postvoid/max (postvoid/maximum count ratio) for whole-kidney and cortical regions of interest and normal ranges for each of these values. Expanded review page also shows enlarged parenchymal image obtained at 2-3 minutes, enlarged display of 19-20 minute image, and quality-control images showing pre- and postinjection syringe counts and time of bolus arrival in kidneys. (QuantEM is software that was developed at Emory University and is licensed by Emory University to GE Healthcare.)

 

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