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Per-Sextant Localization and Staging of Prostate Cancer: Correlation of Imaging Findings with Whole-Mount Step Section Histopathology

Anno Graser1,2, Andreas Heuck2, Bernhard Sommer2, Joerg Massmann1,3, Juergen Scheidler2, Maximillian Reiser1 and Ullrich Mueller-Lisse1

1 Department of Clinical Radiology, University of Munich, Marchioninistrasse 15, Munich 81377, Germany.
2 Radiologisches Zentrum Muenchen-Pasing, Munich, Germany.
3 Present address: Pathologie Lachnerstrasse, Munich, Germany.


Figure 1
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Fig. 1A MR images (A-C) and drawings (D-F) show division of prostate into sextants. Drawings were modified from [16]. Axial T2-weighted fast spin-echo images show division of prostate of 61-year-old man into sextants: right and left bases (A), middle gland (B), and apex (C).

 

Figure 2
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Fig. 1B MR images (A-C) and drawings (D-F) show division of prostate into sextants. Drawings were modified from [16]. Axial T2-weighted fast spin-echo images show division of prostate of 61-year-old man into sextants: right and left bases (A), middle gland (B), and apex (C).

 

Figure 3
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Fig. 1C MR images (A-C) and drawings (D-F) show division of prostate into sextants. Drawings were modified from [16]. Axial T2-weighted fast spin-echo images show division of prostate of 61-year-old man into sextants: right and left bases (A), middle gland (B), and apex (C).

 

Figure 4
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Fig. 1D MR images (A-C) and drawings (D-F) show division of prostate into sextants. Drawings were modified from [16]. Drawing shows base resembles shape of clover leaf and extends from bladder floor to level cranial to axial MR image section with largest transverse diameter of prostate.

 

Figure 5
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Fig. 1E MR images (A-C) and drawings (D-F) show division of prostate into sextants. Drawings were modified from [16]. Drawing shows middle gland resembles shape of ellipse and extends from level of largest transverse diameter of prostate to caudal (inferior) level of verumontanum.

 

Figure 6
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Fig. 1F MR images (A-C) and drawings (D-F) show division of prostate into sextants. Drawings were modified from [16]. Drawing shows apex resembles shape of trapezoid and extends from next caudal level to urogenital diaphragm.

 

Figure 7
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Fig. 2A 61-year-old man with bilateral organ-confined prostate cancer (stage T2c). MR image (A) and whole-mount histopathology image (B) show large tumor focus in left peripheral zone (straight arrow) and smaller foci in right peripheral zone (curved arrow).

 

Figure 8
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Fig. 2B 61-year-old man with bilateral organ-confined prostate cancer (stage T2c). MR image (A) and whole-mount histopathology image (B) show large tumor focus in left peripheral zone (straight arrow) and smaller foci in right peripheral zone (curved arrow).

 

Figure 9
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Fig. 3A Stage T3a prostate cancer with extracapsular extension at left base in 61-year-old man. Axial T2-weighted MR image (A) and whole-mount histopathology image (B) show there is thickening and bulging of prostatic capsule at left base and low-signal-intensity material in neurovascular bundle region (straight arrow). Smaller tumor foci are seen in right peripheral zone (curved arrow).

 

Figure 10
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Fig. 3B Stage T3a prostate cancer with extracapsular extension at left base in 61-year-old man. Axial T2-weighted MR image (A) and whole-mount histopathology image (B) show there is thickening and bulging of prostatic capsule at left base and low-signal-intensity material in neurovascular bundle region (straight arrow). Smaller tumor foci are seen in right peripheral zone (curved arrow).

 

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