Per-Sextant Localization and Staging of Prostate Cancer: Correlation of Imaging Findings with Whole-Mount Step Section Histopathology
Anno Graser1,2,
Andreas Heuck2,
Bernhard Sommer2,
Joerg Massmann1,3,
Juergen Scheidler2,
Maximillian Reiser1 and
Ullrich Mueller-Lisse1
1 Department of Clinical Radiology, University of Munich, Marchioninistrasse 15,
Munich 81377, Germany.
2 Radiologisches Zentrum Muenchen-Pasing, Munich, Germany.
3 Present address: Pathologie Lachnerstrasse, Munich, Germany.

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Fig. 1A MR images (A-C) and drawings (D-F) show
division of prostate into sextants. Drawings were modified from
[16]. Axial T2-weighted fast
spin-echo images show division of prostate of 61-year-old man into sextants:
right and left bases (A), middle gland (B), and apex
(C).
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Fig. 1B MR images (A-C) and drawings (D-F) show
division of prostate into sextants. Drawings were modified from
[16]. Axial T2-weighted fast
spin-echo images show division of prostate of 61-year-old man into sextants:
right and left bases (A), middle gland (B), and apex
(C).
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Fig. 1C MR images (A-C) and drawings (D-F) show
division of prostate into sextants. Drawings were modified from
[16]. Axial T2-weighted fast
spin-echo images show division of prostate of 61-year-old man into sextants:
right and left bases (A), middle gland (B), and apex
(C).
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Fig. 1D MR images (A-C) and drawings (D-F) show
division of prostate into sextants. Drawings were modified from
[16]. Drawing shows base
resembles shape of clover leaf and extends from bladder floor to level cranial
to axial MR image section with largest transverse diameter of prostate.
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Fig. 1E MR images (A-C) and drawings (D-F) show
division of prostate into sextants. Drawings were modified from
[16]. Drawing shows middle
gland resembles shape of ellipse and extends from level of largest transverse
diameter of prostate to caudal (inferior) level of verumontanum.
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Fig. 1F MR images (A-C) and drawings (D-F) show
division of prostate into sextants. Drawings were modified from
[16]. Drawing shows apex
resembles shape of trapezoid and extends from next caudal level to urogenital
diaphragm.
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Fig. 2A 61-year-old man with bilateral organ-confined prostate cancer
(stage T2c). MR image (A) and whole-mount histopathology image
(B) show large tumor focus in left peripheral zone (straight
arrow) and smaller foci in right peripheral zone (curved
arrow).
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Fig. 2B 61-year-old man with bilateral organ-confined prostate cancer
(stage T2c). MR image (A) and whole-mount histopathology image
(B) show large tumor focus in left peripheral zone (straight
arrow) and smaller foci in right peripheral zone (curved
arrow).
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Fig. 3A Stage T3a prostate cancer with extracapsular extension at
left base in 61-year-old man. Axial T2-weighted MR image (A) and
whole-mount histopathology image (B) show there is thickening and
bulging of prostatic capsule at left base and low-signal-intensity material in
neurovascular bundle region (straight arrow). Smaller tumor foci are
seen in right peripheral zone (curved arrow).
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Fig. 3B Stage T3a prostate cancer with extracapsular extension at
left base in 61-year-old man. Axial T2-weighted MR image (A) and
whole-mount histopathology image (B) show there is thickening and
bulging of prostatic capsule at left base and low-signal-intensity material in
neurovascular bundle region (straight arrow). Smaller tumor foci are
seen in right peripheral zone (curved arrow).
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Copyright © 2007 by the American Roentgen Ray Society.