AJR
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Editor's Commentary
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Broome, D. R.
Right arrow Articles by Kirk, G. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Broome, D. R.
Right arrow Articles by Kirk, G. A.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Gadodiamide-Associated Nephrogenic Systemic Fibrosis: Why Radiologists Should Be Concerned

Dale R. Broome1, Mark S. Girguis1, Pedro W. Baron2, Alfred C. Cottrell3, Ingrid Kjellin1 and Gerald A. Kirk1

1 Department of Radiology, Loma Linda University Medical Center, 11234 Anderson St., MC Room 2605, Loma Linda, CA 92354.
2 Department of Surgery, Transplant Division, Loma Linda University Medical Center, Loma Linda, CA.
3 Department of Medicine, Nephrology Division, Loma Linda University Medical Center, Loma Linda, CA.


Figure 1
View larger version (102K):
[in this window]
[in a new window]
[as a PowerPoint slide]
  		Fig. 1A —Two patients with nephrogenic systemic fibrosis (NSF) that developed after gadodiamide injection. Photograph of 46-year-old man shows skin changes due to NSF, including slightly raised and erythematous nodular plaques, and linear and confluent regions of fibrosis.

 

Figure 2
View larger version (86K):
[in this window]
[in a new window]
[as a PowerPoint slide]
  		Fig. 1B —Two patients with nephrogenic systemic fibrosis (NSF) that developed after gadodiamide injection. Photograph of 30-year-old woman with soft-tissue swelling and flexion contractures of hand (with fingers maximally extended) due to NSF.

 

Figure 3
View larger version (48K):
[in this window]
[in a new window]
[as a PowerPoint slide]
  		Fig. 2A —59-year-old man with nephrogenic systemic fibrosis (NSF) with both skeletal muscle and skin findings. Anteroposterior 99mTc HDP 3-hour bone scan shows symmetric increased radionuclide skin and muscle uptake in entire lower extremity and distal upper extremities.

 

Figure 4
View larger version (84K):
[in this window]
[in a new window]
[as a PowerPoint slide]
  		Fig. 2B —59-year-old man with nephrogenic systemic fibrosis (NSF) with both skeletal muscle and skin findings. Axial T1- and fat-suppressed T2-weighted images of thighs show symmetric skin thickening and edema in medial thighs. There is also marked edema in subcutaneous fat, intermuscular fascia, and thigh muscles with some sparing of posterior thigh muscles.

 

Figure 5
View larger version (87K):
[in this window]
[in a new window]
[as a PowerPoint slide]
  		Fig. 2C —59-year-old man with nephrogenic systemic fibrosis (NSF) with both skeletal muscle and skin findings. Axial T1- and fat-suppressed T2-weighted images of thighs show symmetric skin thickening and edema in medial thighs. There is also marked edema in subcutaneous fat, intermuscular fascia, and thigh muscles with some sparing of posterior thigh muscles.

 

Figure 6
View larger version (49K):
[in this window]
[in a new window]
[as a PowerPoint slide]
  		Fig. 3A —30-year-old woman with nephrogenic systemic fibrosis with predominant skin finding. Anteroposterior and lateral 99mTc HDP delayed bone scan shows extensive symmetric skin uptake in lower extremities and distal upper extremities. Uptake is also seen in calf muscles, Achilles tendon, and chest wall.

 

Figure 7
View larger version (37K):
[in this window]
[in a new window]
[as a PowerPoint slide]
  		Fig. 3B —30-year-old woman with nephrogenic systemic fibrosis with predominant skin finding. Anteroposterior and lateral 99mTc HDP delayed bone scan shows extensive symmetric skin uptake in lower extremities and distal upper extremities. Uptake is also seen in calf muscles, Achilles tendon, and chest wall.

 

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?



HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2007 by the American Roentgen Ray Society.