MRI Characterization of Myocardial Tissue in Patients with Fabry's Disease
Massimo Imbriaco1,
Letizia Spinelli2,
Alberto Cuocolo1,
Simone Maurea1,
Giacomo Sica1,
Mario Quarantelli1,
Antonio Pisani3,
Raffaele Liuzzi4,
Bruno Cianciaruso3,
Massimo Sabbatini3 and
Marco Salvatore1
1 Department of Radiology, University Federico II, Via Pansini 5, Via Posillipo
196, Napoli 80123, Italy.
2 Department of Clinical Medicine and Cardiovascular Sciences, University
Federico II, Napoli, Italy.
3 Department of Nephrology, University Federico II, Napoli, Italy.
4 Institute of Biostructure and Bioimaging, University Federico II, Napoli,
Italy.
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Fig. 1A —Graphs show myocardial T2 relaxation times measured in
cardiac areas. Individual data points for myocardial T2 relaxation time (in
milliseconds) measured in septum (A), apex (B), and lateral wall
(C) in three groups of study population; numbers are median values. LV
= left ventricular.
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Fig. 1B —Graphs show myocardial T2 relaxation times measured in
cardiac areas. Individual data points for myocardial T2 relaxation time (in
milliseconds) measured in septum (A), apex (B), and lateral wall
(C) in three groups of study population; numbers are median values. LV
= left ventricular.
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Fig. 1C —Graphs show myocardial T2 relaxation times measured in
cardiac areas. Individual data points for myocardial T2 relaxation time (in
milliseconds) measured in septum (A), apex (B), and lateral wall
(C) in three groups of study population; numbers are median values. LV
= left ventricular.
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Fig. 2A —Four-chamber horizontal long-axis T2-weighted black blood
turbo spin-echo MR images (TR/effective TE, 1,500/75) of subjects from each of
three groups in study population. White circles outline regions of interest in
mid septum, apex, and lateral wall, and corresponding myocardial T2 relaxation
times are shown. 48-year-old man (patient 5 in
Table 1) with Fabry's disease.
Myocardial T2 relaxation times are 86 milliseconds in mid septum, 91
milliseconds in apex, and 90 milliseconds in inferior wall.
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Fig. 2B —Four-chamber horizontal long-axis T2-weighted black blood
turbo spin-echo MR images (TR/effective TE, 1,500/75) of subjects from each of
three groups in study population. White circles outline regions of interest in
mid septum, apex, and lateral wall, and corresponding myocardial T2 relaxation
times are shown. 57-year-old man with left ventricular hypertrophy. Myocardial
T2 relaxation times are 69 milliseconds in mid septum, 67 milliseconds in
apex, and 71 milliseconds in inferior wall.
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Fig. 2C —Four-chamber horizontal long-axis T2-weighted black blood
turbo spin-echo MR images (TR/effective TE, 1,500/75) of subjects from each of
three groups in study population. White circles outline regions of interest in
mid septum, apex, and lateral wall, and corresponding myocardial T2 relaxation
times are shown. Healthy 27-year-old female volunteer. Myocardial T2
relaxation times are 54 milliseconds in mid septum, 51 milliseconds in apex,
and 53 milliseconds in inferior wall.
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Copyright © 2007 by the American Roentgen Ray Society.
