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AJR Teaching File: Diffuse Osteosclerosis with Hepatosplenomegaly

Francis Cloran1 and Kevin P. Banks2

1 Department of Radiology, Wilford Hall Medical Center, Lackland Air Force Base, Lackland, TX.
2 Department of Radiology, Brooke Army Medical Center, MCHE-DR, 3851 Roger Brooke Dr., Fort Sam Houston, TX 78234.


Figure 1
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  		Fig. 1A —59-year-old man with left flank pain. Frontal radiograph of abdomen shows diffuse osteosclerosis and concurrent severe splenomegaly and hepatomegaly.

 

Figure 2
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  		Fig. 1B —59-year-old man with left flank pain. Subsequent contrast-enhanced CT scan of abdomen verifies presence of increased bone density secondary to organized trabecular thickening and deposition along endosteal cortex.

 

Figure 3
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  		Fig. 1C —59-year-old man with left flank pain. Axial T1-weighted MR image through abdomen shows decreased signal intensity of normally bright fatty bone marrow.

 

Figure 4
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  		Fig. 1D —59-year-old man with left flank pain. Coronal T2-weighted MR image through spine reveals homogeneously decreased signal intensity of marrow.

 

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