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Microwave Ablation of Renal Parenchymal Tumors Before Nephrectomy: Phase I Study

Peter E. Clark1,2, Ralph D. Woodruff3, Ronald J. Zagoria4 and M. Craig Hall1,5

1 Department of Urology and Comprehensive Cancer Center of Wake Forest University, Winston-Salem, NC.
2 Present address: Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN.
3 Department of Pathology, Wake Forest University Health Sciences, Winston-Salem, NC.
4 Department of Radiology, Wake Forest University Health Sciences, Medical Center Blvd., Winston-Salem, NC 27157.
5 Present address: Piedmont Urological Associates, High Point, NC.


Figure 1
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Fig. 1A —Photomicrographs show histopathologic features of untreated and treated chromophobe renal cell carcinoma. Area outside ablated tissue zone. Photomicrograph shows normal cellular architecture for this neoplasm. (H and E, x10)

 

Figure 2
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Fig. 1B —Photomicrographs show histopathologic features of untreated and treated chromophobe renal cell carcinoma. Area within ablated tissue zone. Photomicrograph shows abnormalities after ablation including small pyknotic nuclei and reduced cytoplasm. (H and E, x10)

 

Figure 3
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Fig. 1C —Photomicrographs show histopathologic features of untreated and treated chromophobe renal cell carcinoma. Area outside ablated tissue zone. Photomicrograph shows avid staining indicating viable tissue throughout specimen. (Vital stain with reduced nicotinamide adenine dinucleotide [NADH], x10)

 

Figure 4
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Fig. 1D —Photomicrographs show histopathologic features of untreated and treated chromophobe renal cell carcinoma. Area within ablated tissue zone. Photomicrograph shows no significant staining, indicating no viable cells within sample. (Vital stain with NADH, x10)

 

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