Microwave Ablation of Renal Parenchymal Tumors Before Nephrectomy: Phase I Study
Peter E. Clark1,2,
Ralph D. Woodruff3,
Ronald J. Zagoria4 and
M. Craig Hall1,5
1 Department of Urology and Comprehensive Cancer Center of Wake Forest
University, Winston-Salem, NC.
2 Present address: Department of Urologic Surgery, Vanderbilt University Medical
Center, Nashville, TN.
3 Department of Pathology, Wake Forest University Health Sciences,
Winston-Salem, NC.
4 Department of Radiology, Wake Forest University Health Sciences, Medical
Center Blvd., Winston-Salem, NC 27157.
5 Present address: Piedmont Urological Associates, High Point, NC.

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Fig. 1A Photomicrographs show histopathologic features of untreated and
treated chromophobe renal cell carcinoma. Area outside ablated tissue zone.
Photomicrograph shows normal cellular architecture for this neoplasm. (H and
E, x10)
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Fig. 1B Photomicrographs show histopathologic features of untreated and
treated chromophobe renal cell carcinoma. Area within ablated tissue zone.
Photomicrograph shows abnormalities after ablation including small pyknotic
nuclei and reduced cytoplasm. (H and E, x10)
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Fig. 1C Photomicrographs show histopathologic features of untreated and
treated chromophobe renal cell carcinoma. Area outside ablated tissue zone.
Photomicrograph shows avid staining indicating viable tissue throughout
specimen. (Vital stain with reduced nicotinamide adenine dinucleotide [NADH],
x10)
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Fig. 1D Photomicrographs show histopathologic features of untreated and
treated chromophobe renal cell carcinoma. Area within ablated tissue zone.
Photomicrograph shows no significant staining, indicating no viable cells
within sample. (Vital stain with NADH, x10)
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Copyright © 2007 by the American Roentgen Ray Society.