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Renal Pseudotumors

Shweta Bhatt1, Gregory MacLennan2 and Vikram Dogra1

1 Department of Radiology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave., Box 648, Rochester, NY 14642.
2 Department of Pathology, Case Western Reserve University, Cleveland, OH.


Figure 1
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Fig. 1A —46-year-old man with hypertrophied columns (septa) of Bertin. (Reprinted with permission from Paspulati RM, Bhatt S. Sonography in benign and malignant renal masses. Ultrasound Clinics 2006; 1:25-41 [2]) Longitudinal gray-scale sonogram of left kidney shows large hypertrophied columns of Bertin (arrows) located in middle third of kidney. It is continuous with normal renal cortex, and smooth renal surface overlies this pseudotumor.

 

Figure 2
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Fig. 1B —46-year-old man with hypertrophied columns (septa) of Bertin. (Reprinted with permission from Paspulati RM, Bhatt S. Sonography in benign and malignant renal masses. Ultrasound Clinics 2006; 1:25-41 [2]) Follow-up MRI was performed to rule out renal tumor. T1-weighted fat saturated (B) and gadolinium-enhanced (C) images of kidneys confirm presence of hypertrophied columns of Bertin (arrows), which shows similar signal intensity and identical homogeneous enhancement as that of normal renal cortex.

 

Figure 3
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Fig. 1C —46-year-old man with hypertrophied columns (septa) of Bertin. (Reprinted with permission from Paspulati RM, Bhatt S. Sonography in benign and malignant renal masses. Ultrasound Clinics 2006; 1:25-41 [2]) Follow-up MRI was performed to rule out renal tumor. T1-weighted fat saturated (B) and gadolinium-enhanced (C) images of kidneys confirm presence of hypertrophied columns of Bertin (arrows), which shows similar signal intensity and identical homogeneous enhancement as that of normal renal cortex.

 

Figure 4
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Fig. 2 —25-year-old man with dromedary hump. Longitudinal gray-scale sonogram of left kidney shows presence of focal bulge (arrow) on lateral border of left kidney that has similar echotexture as adjacent renal cortex. Adjacent spleen (SP) is visualized, which is causing impression on kidney. (Reprinted with permission from Paspulati RM, Bhatt S. Sonography in benign and malignant renal masses. Ultrasound Clinics 2006; 1:25-41 [2])

 

Figure 5
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Fig. 3 —32-year-old man with persistent fetal lobulation. Longitudinal gray-scale sonogram of right kidney shows sharp indentation (arrow) overlying space between pyramids. Resultant focal bulge on renal surface mimics renal tumor and should be carefully scanned to confirm presence of normal renal tissue within it.

 

Figure 6
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Fig. 4A —53-year-old woman with splenorenal fusion. Axial T1-weighted (A) and coronal T2-weighted (B) MRI images of kidneys show well-defined mass (arrow) in lower pole of left kidney, which is hypointense on T1-weighted and has intermediate signal on T2-weighted images. Multiple renal cysts are also present bilaterally.

 

Figure 7
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Fig. 4B —53-year-old woman with splenorenal fusion. Axial T1-weighted (A) and coronal T2-weighted (B) MRI images of kidneys show well-defined mass (arrow) in lower pole of left kidney, which is hypointense on T1-weighted and has intermediate signal on T2-weighted images. Multiple renal cysts are also present bilaterally.

 

Figure 8
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Fig. 4C —53-year-old woman with splenorenal fusion. Axial (C) and coronal (D) gadolinium-enhanced images of kidneys show intense enhancement of mass (arrow), simulating renal cell carcinoma.

 

Figure 9
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Fig. 4D —53-year-old woman with splenorenal fusion. Axial (C) and coronal (D) gadolinium-enhanced images of kidneys show intense enhancement of mass (arrow), simulating renal cell carcinoma.

 

Figure 10
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Fig. 4E —53-year-old woman with splenorenal fusion. Gross specimen of left kidney after nephrectomy reveals mass consists of hemorrhagic-appearing splenic tissue (SP) in renal capsule but sharply demarcated from adjacent renal parenchyma (K), confirming splenorenal fusion. (Reprinted with permission from Tynski Z, MacLennan GT. Renal pseudotumors. J Urol 2005; 173:600 [1].

 

Figure 11
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Fig. 5 —35-year-old woman with focal pyelonephritis. Contrast-enhanced CT scan of kidneys shows focal hypoattenuating lesion (arrowheads) in right kidney with decreased contrast enhancement. Absence of distinct wall around lesion and clinical information suggestive of infection are helpful in distinguishing this lesion from renal tumor.

 

Figure 12
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Fig. 6A —36-year-old man with left renal abscess. Longitudinal gray-scale sonogram of left kidney shows well-defined hypoechoic mass (arrow) near mid region of kidney.

 

Figure 13
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Fig. 6B —36-year-old man with left renal abscess. Corresponding contrast-enhanced CT scan of kidneys shows low-attenuation mass (arrow) in mid region of left kidney simulating renal cell carcinoma.

 

Figure 14
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Fig. 6C —36-year-old man with left renal abscess. Gross specimen of kidney shows presence of pus and debris in lesion, consistent with abscess (arrowheads).

 

Figure 15
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Fig. 7A —47-year-old woman with xanthogranulomatous pyelonephritis (XGP). Contrast-enhanced CT scans of kidneys show enlarged right kidney with focal area of hypodensity (white arrow, A). Also seen is presence of calculus (arrowhead, B) and part of stent (black arrow, A) in right renal pelvis.

 

Figure 16
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Fig. 7B —47-year-old woman with xanthogranulomatous pyelonephritis (XGP). Contrast-enhanced CT scans of kidneys show enlarged right kidney with focal area of hypodensity (white arrow, A). Also seen is presence of calculus (arrowhead, B) and part of stent (black arrow, A) in right renal pelvis.

 

Figure 17
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Fig. 7C —47-year-old woman with xanthogranulomatous pyelonephritis (XGP). Surgical specimen of kidney (K in C) shows focal XGP (C) and necrotic debris (D). Debris was originally in cavity seen in C.

 

Figure 18
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Fig. 7D —47-year-old woman with xanthogranulomatous pyelonephritis (XGP). Surgical specimen of kidney (K in C) shows focal XGP (C) and necrotic debris (D). Debris was originally in cavity seen in C.

 

Figure 19
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Fig. 7E —47-year-old woman with xanthogranulomatous pyelonephritis (XGP). Microscopic slide shows abundant lipid-laden macrophages (arrowheads), xanthoma cells, with multiple acute and chronic inflammatory cells. (H and E, x40) (Reprinted with permission from Tynski Z, MacLennan GT. Renal pseudotumors. J Urol 2005; 173:600 [1])

 

Figure 20
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Fig. 8A —35-year-old man with renal arteriovenous malformation. Nephrographic phase of contrast-enhanced CT scan of kidneys in this patient with no history of trauma or biopsy shows enhancing lesion in renal pelvis (arrowheads).

 

Figure 21
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Fig. 8B —35-year-old man with renal arteriovenous malformation. Subsequent gray-scale (B) and color Doppler (C) sonograms reveal anechoic structures (arrows, B) in renal pelvis (excluding possibility of solid mass), which fill with color, showing mosaic color-flow pattern with high-velocity, low-impedance pulsatile flow, which is consistent with vascular malformation rather than solid neoplasm.

 

Figure 22
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Fig. 8C —35-year-old man with renal arteriovenous malformation. Subsequent gray-scale (B) and color Doppler (C) sonograms reveal anechoic structures (arrows, B) in renal pelvis (excluding possibility of solid mass), which fill with color, showing mosaic color-flow pattern with high-velocity, low-impedance pulsatile flow, which is consistent with vascular malformation rather than solid neoplasm.

 

Figure 23
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Fig. 9A —35-year-old woman with subepithelial renal pelvic hematomas. Unenhanced CT scan of kidneys shows heterogeneous mass (arrow) in left renal hilum.

 

Figure 24
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Fig. 9B —35-year-old woman with subepithelial renal pelvic hematomas. Corresponding scan during corticomedullary phase of kidneys shows no enhancement of this heterogeneous mass (arrow).

 

Figure 25
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Fig. 9C —35-year-old woman with subepithelial renal pelvic hematomas. Excretory phase scan shows mass effect on collecting system due to left renal hilar mass (arrow).

 

Figure 26
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Fig. 9D —35-year-old woman with subepithelial renal pelvic hematomas. Cut section of surgically removed kidney shows multiple organizing hematomas (arrow) and thromboemboli (arrowhead) in hilar adipose tissue. Pathologic examination showed mass to be subepithelial renal pelvic hematomas secondary to vasculitis.

 

Figure 27
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Fig. 10A —82-year-old woman with renal extramedullary hematopoiesis. Axial (A) and coronal (B) unenhanced CT scans of right kidney show multiple perirenal masses (arrowheads) with severe splenomegaly (SP).

 

Figure 28
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Fig. 10B —82-year-old woman with renal extramedullary hematopoiesis. Axial (A) and coronal (B) unenhanced CT scans of right kidney show multiple perirenal masses (arrowheads) with severe splenomegaly (SP).

 

Figure 29
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Fig. 10C —82-year-old woman with renal extramedullary hematopoiesis. Axial CT scan of pelvis at bone window setting shows coarsening of bone matrix and thinning of cortices, which are suggestive of extramedullary hematopoiesis.

 

Figure 30
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Fig. 10D —82-year-old woman with renal extramedullary hematopoiesis. Microscopy is characterized by presence of megakaryocytes (red arrow) (confirmation by positive immunostaining for factor VIIIra) and granulocyte precursors (blue arrow) (confirmation by positive Leder staining). Presence of these blood cell precursors suggests hematopoietic process in these masses. These microscopic features are confirmatory for extramedullary hematopoiesis. (H and E, x40)

 

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