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Papillary Thyroid Carcinoma Manifested Solely as Microcalcifications on Sonography

Jin Young Kwak1, Eun-Kyung Kim1, Eun Ju Son1, Min Jung Kim1, Ki Keun Oh1, Ji Young Kim2 and Kwang Il Kim2

1 Department of Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine, 134 Shinchon-Dong, Seodaemun-gu, Seoul 120-752, Korea.
2 Department of Pathology, Pochon CHA University College of Medicine, Gyeonggi-do, Korea.


Figure 1
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  		Fig. 1A —53-year-old woman with Graves' disease and diffuse sclerosing variant of papillary carcinoma. Transverse and longitudinal sonograms of right thyroid gland reveal scattered microcalcifications (arrows) and underlying heterogeneous hypoechogenicity.

 

Figure 2
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  		Fig. 1B —53-year-old woman with Graves' disease and diffuse sclerosing variant of papillary carcinoma. Transverse and longitudinal sonograms of right thyroid gland reveal scattered microcalcifications (arrows) and underlying heterogeneous hypoechogenicity.

 

Figure 3
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  		Fig. 1C —53-year-old woman with Graves' disease and diffuse sclerosing variant of papillary carcinoma. Scattered follicular cell clusters show enlarged vesicular nuclei with intranuclear inclusion (arrow). (ThinPrep [Cytyc Corporation], Papanicolaou stain, x400)

 

Figure 4
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  		Fig. 1D —53-year-old woman with Graves' disease and diffuse sclerosing variant of papillary carcinoma. Photomicrograph shows that few psammoma bodies are scattered in diffuse sclerosing variant of papillary carcinoma. (H and E, x200)

 

Figure 5
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  		Fig. 2A —47-year-old woman with thyroid papillary carcinoma and ipsilateral neck node metastasis. Lesion suspected to be thyroid carcinoma was incidentally discovered during sonography intended for evaluation of palpated cervical nodules, which were proven to be benign lymph nodes. Longitudinal sonogram of left thyroid gland reveals multiple microcalcifications (arrows) at low pole and underlying heterogeneous hypoechogenicity.

 

Figure 6
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  		Fig. 2B —47-year-old woman with thyroid papillary carcinoma and ipsilateral neck node metastasis. Lesion suspected to be thyroid carcinoma was incidentally discovered during sonography intended for evaluation of palpated cervical nodules, which were proven to be benign lymph nodes. Transverse sonogram reveals lymph node located at left level IV, measuring 0.7 cm in length, without identifiable structure, indicating fatty hilum (arrows).

 

Figure 7
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  		Fig. 3A —44-year-old woman with thyroid papillary carcinoma incidentally found on thyroid sonography during health examination. Transverse and longitudinal sonograms of right thyroid gland reveal clustered linear microcalcifications (arrows) and underlying heterogeneous hypoechogenicity.

 

Figure 8
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  		Fig. 3B —44-year-old woman with thyroid papillary carcinoma incidentally found on thyroid sonography during health examination. Transverse and longitudinal sonograms of right thyroid gland reveal clustered linear microcalcifications (arrows) and underlying heterogeneous hypoechogenicity.

 

Figure 9
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  		Fig. 3C —44-year-old woman with thyroid papillary carcinoma incidentally found on thyroid sonography during health examination. Sheet of papillary carcinoma shows slightly irregular nuclei with vesicular chromatin and occasional nuclear grooves (arrow). (ThinPrep [Cytyc Corporation], Papanicolaou stain, x1,000)

 

Figure 10
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  		Fig. 3D —44-year-old woman with thyroid papillary carcinoma incidentally found on thyroid sonography during health examination. Photomicrograph shows a few psammoma bodies scattered in papillary carcinoma. (H and E, x200)

 

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