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Dual-Source CT with Improved Temporal Resolution in Assessment of Left Ventricular Function: A Pilot Study

¹ Department of Diagnostic Radiology, Eberhard-Karls-University, Hoppe-Seyler-Str. 3, 72076 Tübingen, Germany.
² Department of Cardiology, Eberhard-Karls-University, Tübingen, Germany.

View larger version (116K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 1A —61-year-old man with known coronary artery disease. Left ventricular endocardial and epicardial contours drawn on reformatted short-axis views using dual-source CT (A and B, respectively) in comparison with cardiac MRI (C and D, respectively) show papillary muscles are included in ventricular volume. Because of use of tube current modulation, there is slight increase in image noise in systole; however, this does not affect differentiation of tissues.

View larger version (124K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 1B —61-year-old man with known coronary artery disease. Left ventricular endocardial and epicardial contours drawn on reformatted short-axis views using dual-source CT (A and B, respectively) in comparison with cardiac MRI (C and D, respectively) show papillary muscles are included in ventricular volume. Because of use of tube current modulation, there is slight increase in image noise in systole; however, this does not affect differentiation of tissues.

View larger version (123K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 1C —61-year-old man with known coronary artery disease. Left ventricular endocardial and epicardial contours drawn on reformatted short-axis views using dual-source CT (A and B, respectively) in comparison with cardiac MRI (C and D, respectively) show papillary muscles are included in ventricular volume. Because of use of tube current modulation, there is slight increase in image noise in systole; however, this does not affect differentiation of tissues.

View larger version (117K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 1D —61-year-old man with known coronary artery disease. Left ventricular endocardial and epicardial contours drawn on reformatted short-axis views using dual-source CT (A and B, respectively) in comparison with cardiac MRI (C and D, respectively) show papillary muscles are included in ventricular volume. Because of use of tube current modulation, there is slight increase in image noise in systole; however, this does not affect differentiation of tissues.

View larger version (14K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 2A —Graphs show time–volume curves. Data are shown for all 20 patients; overall trend is followed by lowest curves. Time–volume curves obtained using dual-source CT (A) and MRI (B).

View larger version (13K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 2B —Graphs show time–volume curves. Data are shown for all 20 patients; overall trend is followed by lowest curves. Time–volume curves obtained using dual-source CT (A) and MRI (B).

View larger version (6K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 3A —Graphs show Bland-Altman analyses comparing global functional parameters obtained using dual-source CT and MRI; x-axis denotes average of dual-source CT (DSCT) and MRI. Point of intersection with y-axis indicates bias of dual-source CT. Dotted lines show SD of bias. Graphs show data for end-diastolic volume (EDV) (A), end-systolic volume (ESV) (B), ejection fraction (EF) (C), and stroke volume (SV) (D).

View larger version (6K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 3B —Graphs show Bland-Altman analyses comparing global functional parameters obtained using dual-source CT and MRI; x-axis denotes average of dual-source CT (DSCT) and MRI. Point of intersection with y-axis indicates bias of dual-source CT. Dotted lines show SD of bias. Graphs show data for end-diastolic volume (EDV) (A), end-systolic volume (ESV) (B), ejection fraction (EF) (C), and stroke volume (SV) (D).

View larger version (5K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 3C —Graphs show Bland-Altman analyses comparing global functional parameters obtained using dual-source CT and MRI; x-axis denotes average of dual-source CT (DSCT) and MRI. Point of intersection with y-axis indicates bias of dual-source CT. Dotted lines show SD of bias. Graphs show data for end-diastolic volume (EDV) (A), end-systolic volume (ESV) (B), ejection fraction (EF) (C), and stroke volume (SV) (D).

View larger version (6K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 3D —Graphs show Bland-Altman analyses comparing global functional parameters obtained using dual-source CT and MRI; x-axis denotes average of dual-source CT (DSCT) and MRI. Point of intersection with y-axis indicates bias of dual-source CT. Dotted lines show SD of bias. Graphs show data for end-diastolic volume (EDV) (A), end-systolic volume (ESV) (B), ejection fraction (EF) (C), and stroke volume (SV) (D).

View larger version (7K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 4A —Graphs show Bland-Altman analyses comparing time-dependent functional parameters obtained using dual-source CT and MRI; x-axis denotes average of dual-source CT (DSCT) and MRI. Point of intersection with y-axis indicates bias of dual-source CT. Graphs show data for peak ejection rate (PER) (A), peak filling rate (PFR) (B), time to PER (C), and time to PFR from end-systole (D).

View larger version (7K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 4B —Graphs show Bland-Altman analyses comparing time-dependent functional parameters obtained using dual-source CT and MRI; x-axis denotes average of dual-source CT (DSCT) and MRI. Point of intersection with y-axis indicates bias of dual-source CT. Graphs show data for peak ejection rate (PER) (A), peak filling rate (PFR) (B), time to PER (C), and time to PFR from end-systole (D).

View larger version (7K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 4C —Graphs show Bland-Altman analyses comparing time-dependent functional parameters obtained using dual-source CT and MRI; x-axis denotes average of dual-source CT (DSCT) and MRI. Point of intersection with y-axis indicates bias of dual-source CT. Graphs show data for peak ejection rate (PER) (A), peak filling rate (PFR) (B), time to PER (C), and time to PFR from end-systole (D).

View larger version (6K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 4D —Graphs show Bland-Altman analyses comparing time-dependent functional parameters obtained using dual-source CT and MRI; x-axis denotes average of dual-source CT (DSCT) and MRI. Point of intersection with y-axis indicates bias of dual-source CT. Graphs show data for peak ejection rate (PER) (A), peak filling rate (PFR) (B), time to PER (C), and time to PFR from end-systole (D).

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