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Colonoscopy Findings in End-Stage Liver Disease Patients with Incidental CT Colonic Wall Thickening

Eleanor L. Ormsby1, Curtis Duffield1, Farshad Ostovar-Sirjani2, John P. McGahan1 and Christoph Troppmann2

1 Department of Radiology, University of California, Davis Medical Center and Lawrence J. Ellison Ambulatory Care Center, 4860 Y St., Ste. 3100, Sacramento, CA 95817.
2 Department of Surgery, University of California, Davis Medical Center, Sacramento, CA 95817.


Figure 1
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Fig. 1A 54-year-old man with hepatitis C end-stage liver disease. CT scan shows diffuse colonic wall thickening extending to left colon. Masslike thickening of ascending colon (long arrow), mildly thickened proximal transverse colon (short arrow), and loss of bowel wall layers are seen.

 

Figure 2
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Fig. 1B 54-year-old man with hepatitis C end-stage liver disease. Colonoscopy shows increased vascularity, especially in cecum and right colon, that is compatible with portal hypertensive colopathy.

 

Figure 3
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Fig. 2A 54-year-old man with end-stage liver disease from hepatitis C and alcoholism. Contrast-enhanced CT scan of abdomen shows markedly thickened and edematous ascending colon, preservation of bowel wall, and stratification of layers (long arrow). Note transverse colon is not affected. Prominent subcutaneous vessels are seen from portosystemic collateralization (short arrow).

 

Figure 4
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Fig. 2B 54-year-old man with end-stage liver disease from hepatitis C and alcoholism. Colonoscopy shows slightly increased chronic inflammatory change and edema of lamina propria. Mucosa was friable and bled easily during examination.

 

Figure 5
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Fig. 3 67-year-old woman with hepatitis C end-stage liver disease. Contrast-enhanced CT scan of abdomen shows stratification of bowel layer (hyperdense inner ring with relative hypodense middle layer, long arrows). Note shaggy mucosa of transverse colon (short arrow). Colonoscopy (not shown) showed mild mucosa edema but was otherwise normal.

 

Figure 6
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Fig. 4 Contrastenhanced CT scan of abdomen in 43-year-old man with end-stage liver disease from hepatitis C and alcoholism shows accordion sign (arrow) and large nodular defects (arrowheads) that are analogous to thumb-printing on radiographs. Colonoscopy (not shown) was normal except for mucosal edema.

 

Figure 7
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Fig. 5A 60-year-old man with colonic thickening, ulcerative colitis, and primary sclerosing cholangitis. Contrast-enhanced CT scan of abdomen shows diffuse concentric thickening of right and left colon. Minimal preservation of mucosa (arrow) was seen. Note large ascites and portosystemic collateral vessel (arrowhead).

 

Figure 8
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Fig. 5B 60-year-old man with colonic thickening, ulcerative colitis, and primary sclerosing cholangitis. CT scan of pelvis shows diffuse colonic thickening involving rectosigmoid colon (arrow), ascites, and mesenteric stranding. Note this colonic thickening is less in this region than in right colon as seen in A.

 

Figure 9
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Fig. 5C 60-year-old man with colonic thickening, ulcerative colitis, and primary sclerosing cholangitis. Colonoscopy shows diffuse mucosal erythema and superficial ulcers indicative of moderate to severe active ulcerative colitis.

 

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