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Prediction of Mortality and Need for Neonatal Extracorporeal Membrane Oxygenation in Fetuses with Congenital Diaphragmatic Hernia: Logistic Regression Analysis Based on MRI Fetal Lung Volume Measurements

K. Wolfgang Neff1, A. Kristina Kilian1, Thomas Schaible2, Eva-Maria Schütz1 and Karen A. Büsing1

1 Department of Clinical Radiology, University Hospital Mannheim, University of Heidelberg, Theodor Kutzer Ufer 1-3, 68167 Mannheim, Germany.
2 Department of Pediatrics, University Hospital Mannheim, University of Heidelberg, Mannheim, Germany.


Figure 1
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  		Fig. 1A —Fetus at 33 weeks of gestation. Coronal MR images obtained with HASTE sequence show fetal lung.

 

Figure 2
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  		Fig. 1B —Fetus at 33 weeks of gestation. Coronal MR images obtained with HASTE sequence show fetal lung.

 

Figure 3
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  		Fig. 1C —Fetus at 33 weeks of gestation. Transverse MR images obtained with true fast imaging with steady-state precession sequence and used for fetal lung volume assessment show fetal lung differentiated from heart (single asterisk) and herniated abdominal contents including fetal liver (double asterisk). Region of interest follows lung boundaries and does not include main vessels of pulmonary hila. Regions of interest with lung planimetry are shown in B and D.

 

Figure 4
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  		Fig. 1D —Fetus at 33 weeks of gestation. Transverse MR images obtained with true fast imaging with steady-state precession sequence and used for fetal lung volume assessment show fetal lung differentiated from heart (single asterisk) and herniated abdominal contents including fetal liver (double asterisk). Region of interest follows lung boundaries and does not include main vessels of pulmonary hila. Regions of interest with lung planimetry are shown in B and D.

 

Figure 5
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  		Fig. 2 —Graph shows results of logistic regression analysis of mortality and probability of need for neonatal extracorporeal membrane oxygenation (ECMO).

 

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