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Dynamic Contrast Enhancement Patterns of Solitary Pulmonary Nodules on 3D Gradient-Recalled Echo MRI

Fuldem Yildirim Donmez1,2, Ensar Yekeler1, Violet Saeidi1, Atadan Tunaci1, Mehtap Tunaci1 and Gulden Acunas1

1 Department of Radiology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
2 Present address: Department of Radiology, Baskent University, Faculty of Medicine, 46 Sokak No. 11/8 Yuksel Apt, 06500, Bahcelievler, Ankara, Turkey.


Figure 1
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Fig. 1A 48-year-old man with adenocarcinoma of left lung. Dynamic contrast-enhanced 3D fast low-angle shot images (TR/TE, 5.2/2.5; flip angle, 10°; slab thickness, 78–96 mm; slice thickness, 3 mm; matrix size, 196 x 256) show peripheral enhancement with progressive heterogeneous fill-in of left apical lung cancer.

 

Figure 2
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Fig. 1B 48-year-old man with adenocarcinoma of left lung. Dynamic contrast-enhanced 3D fast low-angle shot images (TR/TE, 5.2/2.5; flip angle, 10°; slab thickness, 78–96 mm; slice thickness, 3 mm; matrix size, 196 x 256) show peripheral enhancement with progressive heterogeneous fill-in of left apical lung cancer.

 

Figure 3
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Fig. 1C 48-year-old man with adenocarcinoma of left lung. Dynamic contrast-enhanced 3D fast low-angle shot images (TR/TE, 5.2/2.5; flip angle, 10°; slab thickness, 78–96 mm; slice thickness, 3 mm; matrix size, 196 x 256) show peripheral enhancement with progressive heterogeneous fill-in of left apical lung cancer.

 

Figure 4
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Fig. 1D 48-year-old man with adenocarcinoma of left lung. Dynamic contrast-enhanced 3D fast low-angle shot images (TR/TE, 5.2/2.5; flip angle, 10°; slab thickness, 78–96 mm; slice thickness, 3 mm; matrix size, 196 x 256) show peripheral enhancement with progressive heterogeneous fill-in of left apical lung cancer.

 

Figure 5
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Fig. 1E 48-year-old man with adenocarcinoma of left lung. Dynamic contrast-enhanced 3D fast low-angle shot images (TR/TE, 5.2/2.5; flip angle, 10°; slab thickness, 78–96 mm; slice thickness, 3 mm; matrix size, 196 x 256) show peripheral enhancement with progressive heterogeneous fill-in of left apical lung cancer.

 

Figure 6
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Fig. 1F 48-year-old man with adenocarcinoma of left lung. Dynamic contrast-enhanced 3D fast low-angle shot images (TR/TE, 5.2/2.5; flip angle, 10°; slab thickness, 78–96 mm; slice thickness, 3 mm; matrix size, 196 x 256) show peripheral enhancement with progressive heterogeneous fill-in of left apical lung cancer.

 

Figure 7
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Fig. 1G 48-year-old man with adenocarcinoma of left lung. Time–signal intensity curve obtained from periphery of lesion in A shows type A pattern (early increasing enhancement with rapid washout).

 

Figure 8
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Fig. 2A 45-year-old man with adenocarcinoma of right lung. Dynamic contrast-enhanced 3D fast low-angle shot late-phase image (TR/TE, 5.2/2.5; flip angle, 10°; slab thickness, 78–96 mm; slice thickness, 3 mm; matrix size, 196 x 256) shows diffusely enhancing mass (arrows) on posterobasal segment of right lung.

 

Figure 9
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Fig. 2B 45-year-old man with adenocarcinoma of right lung. Time–signal intensity curve obtained from lesion in A shows type D pattern (gradually increasing enhancement).

 

Figure 10
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Fig. 3A 52-year-old woman with tuberculosis. Dynamic contrast-enhanced 3D fast low-angle shot image (TR/TE, 5.2/2.5; flip angle, 10°; slab thickness, 78–96 mm; slice thickness, 3 mm; matrix size, 196 x 256) shows rim enhancement of left apical tuberculoma (arrows).

 

Figure 11
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Fig. 3B 52-year-old woman with tuberculosis. Time–signal intensity curve obtained from rim of tuberculoma in A depicts type B pattern (early increasing enhancement with early plateau at second minute).

 

Figure 12
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Fig. 4A 56-year-old man with round atelectasis. Dynamic contrast-enhanced 3D fast low-angle shot image (TR/TE, 5.2/2.5; flip angle, 10°; slab thickness, 78–96 mm; slice thickness, 3 mm; matrix size, 196 x 256) shows intense homogeneous enhancement of round atelectasis lesion (arrow).

 

Figure 13
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Fig. 4B 56-year-old man with round atelectasis. Time–signal intensity curve obtained from lesion in A shows type C pattern (early increasing enhancement with late plateau at fourth minute).

 

Figure 14
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Fig. 5 Algorithm for evaluation of solitary pulmonary nodules.

 

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