Measurement of Serum Calcium Concentration After Administration of Four Gadolinium-Based Contrast Agents to Human Volunteers
Jeffery J. Brown1,
Michael R. Hynes2 and
James H. Wible, Jr.2
1 Mallinckrodt Institute of Radiology, Washington University, St. Louis,
MO. 2 Covidien/Mallinckrodt Imaging, PO Box 5840, 675 McDonnell Blvd., Saint Louis,
MO 63134.
Fig. 1—Effects of gadoversetamide (0.1 mmol/kg) on measurement of
serum calcium. Values represent mean and standard error of mean (n =
12). Asterisks denote statistically significant (p < 0.05)
differences from baseline. Diamonds indicate orthocresolphthalein; squares,
arsenazo III; circles, inductively coupled plasma mass spectrometry.
Fig. 2—Effects of gadodiamide (0.1 mmol/kg) on measurement of serum
calcium. Values represent mean and standard error of mean (n = 12).
Asterisks denote statistically significant (p < 0.05) differences
from baseline. Diamonds indicate orthocresolphthalein; squares, arsenazo III;
circles, inductively coupled plasma mass spectrometry.
Fig. 3A—Effects of gadopentetate and gadoteridol on measurement of
serum calcium. Values represent mean and standard error of mean (n =
12). Diamonds indicate orthocresolphthalein; squares, arsenazo III; circles,
inductively coupled plasma mass spectrometry. Gadopentetate 0.1 mmol/kg.
Fig. 3B—Effects of gadopentetate and gadoteridol on measurement of
serum calcium. Values represent mean and standard error of mean (n =
12). Diamonds indicate orthocresolphthalein; squares, arsenazo III; circles,
inductively coupled plasma mass spectrometry. Gadoteridol 0.1 mmol/kg.