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3-T MRI in the Preoperative Evaluation of Depth of Myometrial Infiltration in Endometrial Cancer

Pietro Torricelli1, Sonia Ferraresi1, Federica Fiocchi1, Guido Ligabue1, Valerio M. Jasonni2, Ilaria Di Monte2 and Francesco Rivasi3

1 Department of Radiology, University of Modena and Reggio-Emilia, Policlinico, Via del Pozzo 71, 41100 Modena, Italy.
2 Department of Gynecology, University of Modena and Reggio-Emilia, Modena, Italy.
3 Department of Pathology, University of Modena and Reggio-Emilia, Modena, Italy.


Figure 1
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Fig. 1A 52-year-old woman with stage IB endometrial carcinoma. Sagittal (A) and coronal (B) fast spin-echo T2-weighted images show huge endometrial tumor that enlarges endometrial cavity. In anteroinferior part of uterus body, junctional zone (arrow) is thinned and not clearly visible. Myometrium is thinned to less than 50% of its thickness. Multiple uterine fibroids are present.

 

Figure 2
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Fig. 1B 52-year-old woman with stage IB endometrial carcinoma. Sagittal (A) and coronal (B) fast spin-echo T2-weighted images show huge endometrial tumor that enlarges endometrial cavity. In anteroinferior part of uterus body, junctional zone (arrow) is thinned and not clearly visible. Myometrium is thinned to less than 50% of its thickness. Multiple uterine fibroids are present.

 

Figure 3
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Fig. 1C 52-year-old woman with stage IB endometrial carcinoma. Paracoronal gadolinium-enhanced T1-weighted image in arterial phase shows subendometrial enhancement line in anteroinferior part is thinned and irregular but is continuous. These findings suggest that myometrial infiltration is less than 50%.

 

Figure 4
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Fig. 2A 56-year-old woman with stage IB endometrial carcinoma. Sagittal fast spin-echo T2-weighted image shows endometrial cavity is occupied by hypointense mass that causes thinning of junctional zone (arrow) in inferior part of uterine body.

 

Figure 5
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Fig. 2B 56-year-old woman with stage IB endometrial carcinoma. Paracoronal gadolinium-enhanced T1-weighted images in arterial (B) and late (C) phases show that subendometrial enhancement line is irregularly enhanced but is continuous. These findings suggest superficial invasion of myometrium.

 

Figure 6
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Fig. 2C 56-year-old woman with stage IB endometrial carcinoma. Paracoronal gadolinium-enhanced T1-weighted images in arterial (B) and late (C) phases show that subendometrial enhancement line is irregularly enhanced but is continuous. These findings suggest superficial invasion of myometrium.

 

Figure 7
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Fig. 3A 59-year-old woman with stage IC endometrial carcinoma. Sagittal fast spin-echo T2-weighted image shows large, lobulated, and hypointense mass completely interrupting junctional zone (arrow) and deeply invading myometrium. Multiple fibroids are also visible. Extent of myometrial invasion was assessed as more than 50%.

 

Figure 8
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Fig. 3B 59-year-old woman with stage IC endometrial carcinoma. Axial gadolinium-enhanced T1-weighted MR images in arterial (B) and late (C) phases confirm hypointense mass has invaded more than 50% of myometrium thickness (arrowhead).

 

Figure 9
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Fig. 3C 59-year-old woman with stage IC endometrial carcinoma. Axial gadolinium-enhanced T1-weighted MR images in arterial (B) and late (C) phases confirm hypointense mass has invaded more than 50% of myometrium thickness (arrowhead).

 

Figure 10
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Fig. 4A 57-year-old woman with stage IC endometrial carcinoma. Sagittal fast spin-echo T2-weighted image shows slightly hyperintense tumor deeply invading myometrium (arrow) in inferior part of uterine body. Junctional zone is not visible. Cervical nabothian cyst is also visible.

 

Figure 11
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Fig. 4B 57-year-old woman with stage IC endometrial carcinoma. Paracoronal gadolinium-enhanced T1-weighted image in late phase shows better than A that transmyometrial infiltration of tumor reaches serosa in anterior part of uterine corpus (arrowhead).

 

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