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Is There Sufficient MDCT Capacity to Provide Colorectal Cancer Screening with CT Colonography for the U.S. Population?

Perry J. Pickhardt1,2, Cesare Hassan3, Andrea Laghi4, David H. Kim1, Angelo Zullo3, Franco Iafrate4 and Sergio Morini3

1 Department of Radiology, University of Wisconsin Medical School, E3/311 Clinical Science Center, 600 Highland Ave., Madison, WI 53792-3252.
2 Department of Radiology, Uniformed Services University of the Health Sciences, Bethesda, MD.
3 Gastroenterology and Digestive Endoscopy Unit, "Nuovo Regina Margherita" Hospital, Rome, Italy.
4 Department of Radiological Sciences, University of Rome La Sapienza "Policlinico Umberto I," Rome, Italy.


Figure 1
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  		Fig. 1 —Graph of sensitivity analysis (startup period) shows variation of mean number of CT colonography (CTC) examinations needed to be performed by each MDCT unit per day to screen U.S. population according to overall screening compliance and specific CTC penetrance. Solid vertical line indicates baseline. Dashed line indicates number of CTC/MDCT/day at baseline assumptions. Baseline penetrance = {diamondsuit}, 30% penetrance = {blacksquare}, -30% penetrance = {blacktriangleup}.

 

Figure 2
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  		Fig. 2 —Graph of sensitivity analysis (startup period) shows variation of mean number of CT colonography (CTC) examinations needed to be performed by each MDCT unit per day to screen U.S. population according to MDCT capacity and overall screening compliance. Solid vertical line indicates baseline. Dashed line indicates number of CTC/MDCT/day at baseline assumptions. Baseline compliance = {blacktriangleup}, 30% compliance = {blacksquare}, 85% compliance = {diamondsuit}.

 

Figure 3
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  		Fig. 3 —Graph of sensitivity analysis (steady-state period) shows variation of mean number of CT colonography (CTC) examinations needed to be performed by each MDCT unit per day to screen U.S. population according to initial overall screening compliance and specific compliance to 5-year repeated CTC examination. Solid vertical line indicates baseline. Dashed line indicates number of CTC/MDCT/day at baseline assumptions. Baseline repeating compliance = {diamondsuit}, 25% repeating compliance = {blacksquare}, 75% repeating compliance = {blacktriangleup}.

 

Figure 4
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  		Fig. 4 —Graph of sensitivity analysis (steady-state period) shows variation of mean number of CT colonography (CTC) examinations needed to be performed by each MDCT unit per day to screen U.S. population according to MDCT capacity and overall screening compliance. Solid vertical line indicates baseline. Dashed line indicates number of CTC/MDCT/day at baseline assumptions. Baseline compliance = {blacktriangleup}, 30% compliance = {blacksquare}, 85% compliance = {diamondsuit}.

 

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