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Coronary Arterial Calcification on Low-Dose Ungated MDCT for Lung Cancer Screening: Concordance Study with Dedicated Cardiac CT

Ming-Ting Wu1,2, Pinchen Yang3, Yi-Luan Huang1,2, Jian-Shyong Chen2, Chiung-Chen Chuo2, Chinson Yeh4 and Ruey-Sheng Chang2,5

1 Faculty of Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan, Republic of China.
2 Section of Thoracic and Circulation Imaging, Department of Radiology, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st Rd., Kaohsiung, Taiwan 813, Republic of China.
3 Department of Psychiatry, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China.
4 Department of Mechanical and Electromechanical Engineering, National Sun-Yat Sen University, Kaohsiung, Tainan, Taiwan, Republic of China.
5 Department of Radiology, National Cheng Kung University, Tainan, Taiwan, Republic of China.


Figure 1
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Fig. 1A 82-year-old man with true-positive prediction of coronary artery calcification (CAC) on low-dose ungated MDCT. Regular-dose ECG-gated MDCT scans show CAC on left anterior descending artery (arrow, A); CAC score is 305. Aortic wall calcification (arrowhead, A) also is present. CAC on right coronary artery (arrow, B) has score of 25. Total CAC score is 551.

 

Figure 2
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Fig. 1B 82-year-old man with true-positive prediction of coronary artery calcification (CAC) on low-dose ungated MDCT. Regular-dose ECG-gated MDCT scans show CAC on left anterior descending artery (arrow, A); CAC score is 305. Aortic wall calcification (arrowhead, A) also is present. CAC on right coronary artery (arrow, B) has score of 25. Total CAC score is 551.

 

Figure 3
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Fig. 1C 82-year-old man with true-positive prediction of coronary artery calcification (CAC) on low-dose ungated MDCT. Low-dose ungated MDCT scans show CAC on left anterior descending artery (arrow, C) and right coronary artery (arrow, D). Aortic wall calcification (arrowhead, C) also is present. CAC scores are 274 in C, 15 in D, 508 total.

 

Figure 4
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Fig. 1D 82-year-old man with true-positive prediction of coronary artery calcification (CAC) on low-dose ungated MDCT. Low-dose ungated MDCT scans show CAC on left anterior descending artery (arrow, C) and right coronary artery (arrow, D). Aortic wall calcification (arrowhead, C) also is present. CAC scores are 274 in C, 15 in D, 508 total.

 

Figure 5
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Fig. 2A 72-year-old man with false-negative prediction of coronary artery calcification (CAC) on low-dose ungated MDCT. Regular-dose ECG-gated MDCT scan clearly shows CAC on right coronary artery (arrow); CAC score is 2.

 

Figure 6
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Fig. 2B 72-year-old man with false-negative prediction of coronary artery calcification (CAC) on low-dose ungated MDCT. Low-dose ungated MDCT scan shows faint attenuation (arrow) only; CAC score is 0.

 

Figure 7
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Fig. 3A 46-year-old 79-kg man with false-positive prediction of coronary artery calcification (CAC) on low-dose ungated MDCT. Regular-dose ECG-gated MDCT scan shows no CAC on right coronary artery (arrow).

 

Figure 8
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Fig. 3B 46-year-old 79-kg man with false-positive prediction of coronary artery calcification (CAC) on low-dose ungated MDCT. Low-dose ungated MDCT scan shows several high-attenuation spots (arrow) over atrioventricular groove, assumed to be on pathway of right coronary artery; CAC score is 3. Noise level at aortic root is much higher on low-dose ungated MDCT (SD = 29.7) than on regular-dose ECG-gated MDCT (SD = 14.7).

 

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