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Hypervascular Thyroid Nodules on Time-Resolved MR Angiography at 3 T: Radiologic–Pathologic Correlation

¹ All authors: Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Peter V. Ueberroth Bldg., Ste. 3371, 10945 Le Conte Ave., Los Angeles, CA 90095-7206.

View larger version (64K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 1A —47-year-old woman with isthmic hypervascular thyroid nodule (bold region of interest in A). Single arterial phase image from dynamic time-resolved MR angiography reveals conspicuity of this enhancing lesion.

View larger version (10K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 1B —47-year-old woman with isthmic hypervascular thyroid nodule (bold region of interest in A). Graph shows dynamic enhancement curves for hypervascular nodule and normal thyroid parenchyma. Note more rapid time-to-peak (image number 7) and overall higher signal intensity for hypervascular nodule compared with thyroid parenchyma.

View larger version (52K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 2A —45-year-old woman with incidentally noted left thyroid hypervascular nodule, subsequently diagnosed as papillary carcinoma. Sequential frames from time-resolved MR angiography reveal presence of relatively more rapid and more intense nodular enhancement (arrows).

View larger version (57K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 2B —45-year-old woman with incidentally noted left thyroid hypervascular nodule, subsequently diagnosed as papillary carcinoma. Sequential frames from time-resolved MR angiography reveal presence of relatively more rapid and more intense nodular enhancement (arrows).

View larger version (57K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 2C —45-year-old woman with incidentally noted left thyroid hypervascular nodule, subsequently diagnosed as papillary carcinoma. Sequential frames from time-resolved MR angiography reveal presence of relatively more rapid and more intense nodular enhancement (arrows).

View larger version (56K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 2D —45-year-old woman with incidentally noted left thyroid hypervascular nodule, subsequently diagnosed as papillary carcinoma. Sequential frames from time-resolved MR angiography reveal presence of relatively more rapid and more intense nodular enhancement (arrows).

View larger version (54K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 2E —45-year-old woman with incidentally noted left thyroid hypervascular nodule, subsequently diagnosed as papillary carcinoma. Sequential frames from time-resolved MR angiography reveal presence of relatively more rapid and more intense nodular enhancement (arrows).

View larger version (52K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 2F —45-year-old woman with incidentally noted left thyroid hypervascular nodule, subsequently diagnosed as papillary carcinoma. Sequential frames from time-resolved MR angiography reveal presence of relatively more rapid and more intense nodular enhancement (arrows).

View larger version (87K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 2G —45-year-old woman with incidentally noted left thyroid hypervascular nodule, subsequently diagnosed as papillary carcinoma. Duplex Doppler sonogram (G) confirms presence of nodular vascularity. Note isoattenuation of this lesion compared with adjacent thyroid parenchyma on blood-pool phase CT (H), with markers (red) showing extent of thyroid nodule.

View larger version (61K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 2H —45-year-old woman with incidentally noted left thyroid hypervascular nodule, subsequently diagnosed as papillary carcinoma. Duplex Doppler sonogram (G) confirms presence of nodular vascularity. Note isoattenuation of this lesion compared with adjacent thyroid parenchyma on blood-pool phase CT (H), with markers (red) showing extent of thyroid nodule.

View larger version (65K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 3A —38-year-old man with hyperplastic thyroid nodule (arrows). Note presence of peripheral hyperenhancement on arterial phase image (A), with loss of lesion definition on subsequent image (B) acquired only 3.6 seconds later. Loss of definition is due to relatively delayed thyroid parenchymal enhancement in B.

View larger version (65K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 3B —38-year-old man with hyperplastic thyroid nodule (arrows). Note presence of peripheral hyperenhancement on arterial phase image (A), with loss of lesion definition on subsequent image (B) acquired only 3.6 seconds later. Loss of definition is due to relatively delayed thyroid parenchymal enhancement in B.

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