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Using CT Enterography to Monitor Crohn's Disease Activity: A Preliminary Study

Amy K. Hara1, Shayan Alam2, Russell I. Heigh3, Suryakanth R. Gurudu3, Joseph G. Hentz4 and Jonathan A. Leighton3

1 Department of Diagnostic Radiology, Mayo Clinic, 13400 E Shea Blvd., Scottsdale, AZ 85259.
2 Department of Internal Medicine, Mayo Clinic, Scottsdale, AZ.
3 Division of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ.
4 Division of Biostatistics, Mayo Clinic, Scottsdale, AZ.


Figure 1
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  		Fig. 1A —72-year-old woman with Crohn's disease. Initial axial CT enterography image shows normal enhancement and thickness of ileum and cecum (oval).

 

Figure 2
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  		Fig. 1B —72-year-old woman with Crohn's disease. Axial CT enterography image obtained 11 months later after patient complained of increasing abdominal pain and diarrhea. Increased thickening and enhancement in same ileal loop and cecum (oval) indicate activeCrohn's disease.

 

Figure 3
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  		Fig. 2A —83-year-old man with Crohn's disease. Initial coronal CT enterography image shows ileum of normal thickness (oval).

 

Figure 4
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  		Fig. 2B —83-year-old man with Crohn's disease. Follow-up coronal CT enterography image obtained 19 months later after patient complained of increasing abdominal pain and diarrhea. CT enterography shows new wall thickening and enhancement in ileum (oval), typical of active Crohn's disease.

 

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