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Pulmonary Embolism Outcome: A Prospective Evaluation of CT Pulmonary Angiographic Clot Burden Score and ECG Score

Rathan M. Subramaniam1,2, Jay Mandrekar3, Catherine Chang4, Damon Blair1, Kevin Gilbert1, Patrick J. Peller2, Jamie Sleigh5 and Noel Karalus4

1 Department of Radiology, Waikato Hospital and Waikato Clinical School, University of Auckland, Hamilton, New Zealand.
2 Department of Radiology, Mayo Clinic and Mayo College of Medicine, 200 1st St. SW, Rochester, MN 55905.
3 Department of Biostatistics and Health Services Research, Mayo Clinic and Mayo College of Medicine, Rochester, MN.
4 Department of Respiratory Medicine, Waikato Hospital, Hamilton, New Zealand.
5 Department of Intensive Care, Waikato Hospital and Waikato Clinical School, University of Auckland, Hamilton, New Zealand.


Figure 1
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  		Fig. 1 —Clot burden score percentages calculated by reader 1 are plotted on y-axis and those calculated by reader 2 on x-axis. Intraclass correlation was 0.91 (95% CI, 0.89-0.92); Spearman's correlation was 0.72 (p < 0.0001).

 

Figure 2
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  		Fig. 2 —Outcome at 12-month follow-up and average clot burden score percentage (p < 0.73).

 

Figure 3
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  		Fig. 3 —ECG scores calculated by reader 1 are plotted on y-axis and those calculated by reader 2 on x-axis. Intraclass correlation was 0.96 (95% CI, 0.95-0.96); Pearson's correlation was r = 0.89 (p < 0.0001).

 

Figure 4
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  		Fig. 4 —Outcome at 12-month follow-up and average ECG score (p < 0.23).

 

Figure 5
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  		Fig. 5 —Average ECG scores and three categories of CT pulmonary angiographic clot burden score (< 30%, 30-50%, and > 50%).

 

Figure 6
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  		Fig. 6 —Scatterplot shows poor correlation between average ECG score and average clot burden score percentage (r = 0.09; p = 0.39).

 

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