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MDCT of the Breast

Anna Perrone1, Luigi Lo Mele1, Simona Sassi1, Marina Marini1, Lorenzo Testaverde1, Luciano Izzo2 and Mario Marini1

1 Department of Radiological Sciences, University La Sapienza of Rome-Policlinico Umberto I, Via Regina Elena, 324, 00161 Rome, Italy.
2 Department of Surgical Sciences, University La Sapienza of Rome-Policlinico Umberto I, Rome, Italy.


Figure 1
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Fig. 1A 58-year-old woman with phyllodes tumor in left breast. Dynamic MDCT scans at baseline (A) and 1 minute after contrast administration (B) show large, regular lesion with early and intense enhancement in most of breast.

 

Figure 2
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Fig. 1B 58-year-old woman with phyllodes tumor in left breast. Dynamic MDCT scans at baseline (A) and 1 minute after contrast administration (B) show large, regular lesion with early and intense enhancement in most of breast.

 

Figure 3
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Fig. 2A 46-year-old woman with nonspecific inflammatory tissue in right breast. Dynamic MDCT scans at baseline (A) and 1 minute after contrast administration (B) show thickened homogeneous tissue beneath nipple, which exhibited strong enhancement.

 

Figure 4
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Fig. 2B 46-year-old woman with nonspecific inflammatory tissue in right breast. Dynamic MDCT scans at baseline (A) and 1 minute after contrast administration (B) show thickened homogeneous tissue beneath nipple, which exhibited strong enhancement.

 

Figure 5
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Fig. 3A 72-year-old woman with ductal carcinoma in situ in left breast approximately 2.5 cm behind nipple. Dynamic MDCT images obtained 1 (A) and 8 (B) minutes after contrast administration show very small ({approx} 4 mm) smooth lesion with homogeneous enhancement; time-attenuation curve was washout type.

 

Figure 6
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Fig. 3B 72-year-old woman with ductal carcinoma in situ in left breast approximately 2.5 cm behind nipple. Dynamic MDCT images obtained 1 (A) and 8 (B) minutes after contrast administration show very small ({approx} 4 mm) smooth lesion with homogeneous enhancement; time-attenuation curve was washout type.

 

Figure 7
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Fig. 4 Graph shows time-attenuation curve of absolute values for benign versus malignant lesions.

 

Figure 8
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Fig. 5 Graph shows time-attenuation curve of percentage values for benign versus malignant lesions.

 

Figure 9
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Fig. 6A 52-year-old woman with invasive ductal carcinoma in left breast. Dynamic MDCT images at baseline (A) and 1 minute (B) after contrast administration depict irregular lesion with homogeneous enhancement; evaluation of time-attenuation curve showed washout pattern.

 

Figure 10
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Fig. 6B 52-year-old woman with invasive ductal carcinoma in left breast. Dynamic MDCT images at baseline (A) and 1 minute (B) after contrast administration depict irregular lesion with homogeneous enhancement; evaluation of time-attenuation curve showed washout pattern.

 

Figure 11
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Fig. 6C 52-year-old woman with invasive ductal carcinoma in left breast. Coronal and sagittal multiplanar reconstructions 1 minute after contrast administration show lesion in A and B located in upper left quadrant of breast, approximately 2 cm behind nipple.

 

Figure 12
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Fig. 6D 52-year-old woman with invasive ductal carcinoma in left breast. Coronal and sagittal multiplanar reconstructions 1 minute after contrast administration show lesion in A and B located in upper left quadrant of breast, approximately 2 cm behind nipple.

 

Figure 13
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Fig. 7A 50-year-old woman with fibroadenoma in right breast. Dynamic MDCT scans show lesion with smooth margins and sustained and increasing enhancement (A, baseline; B, at 1 minute after contrast administration; C, at 3 minutes; D, at 8 minutes) in upper outer quadrant of breast.

 

Figure 14
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Fig. 7B 50-year-old woman with fibroadenoma in right breast. Dynamic MDCT scans show lesion with smooth margins and sustained and increasing enhancement (A, baseline; B, at 1 minute after contrast administration; C, at 3 minutes; D, at 8 minutes) in upper outer quadrant of breast.

 

Figure 15
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Fig. 7C 50-year-old woman with fibroadenoma in right breast. Dynamic MDCT scans show lesion with smooth margins and sustained and increasing enhancement (A, baseline; B, at 1 minute after contrast administration; C, at 3 minutes; D, at 8 minutes) in upper outer quadrant of breast.

 

Figure 16
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Fig. 7D 50-year-old woman with fibroadenoma in right breast. Dynamic MDCT scans show lesion with smooth margins and sustained and increasing enhancement (A, baseline; B, at 1 minute after contrast administration; C, at 3 minutes; D, at 8 minutes) in upper outer quadrant of breast.

 

Figure 17
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Fig. 8 Graph shows distribution of attenuation values under basal conditions for malignant (light gray) versus benign (dark gray) lesion groups.

 

Figure 18
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Fig. 9 Graph shows distribution of attenuation values 1 minute after contrast administration for malignant (light gray) versus benign (dark gray) lesion groups.

 

Figure 19
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Fig. 10 Graph shows distribution of attenuation values 3 minutes after contrast administration for malignant (light gray) versus benign (dark gray) lesion groups.

 

Figure 20
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Fig. 11 Graph shows distribution of attenuation values 8 minutes after contrast administration for malignant (light gray) versus benign (dark gray) lesion groups.

 

Figure 21
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Fig. 12A 54-year-old woman with invasive ductal carcinoma in upper inner quadrant of right breast. Dynamic MDCT images at baseline (A) and 1 (B), 3 (C), and 8 (D) minutes after contrast administration depict spiculated lesion with low enhancement 1 minute after contrast administration. Lesion was only one in study with value less than 90 H 1 minute after contrast administration; evaluation of time-attenuation curve, however, showed washout pattern.

 

Figure 22
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Fig. 12B 54-year-old woman with invasive ductal carcinoma in upper inner quadrant of right breast. Dynamic MDCT images at baseline (A) and 1 (B), 3 (C), and 8 (D) minutes after contrast administration depict spiculated lesion with low enhancement 1 minute after contrast administration. Lesion was only one in study with value less than 90 H 1 minute after contrast administration; evaluation of time-attenuation curve, however, showed washout pattern.

 

Figure 23
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Fig. 12C 54-year-old woman with invasive ductal carcinoma in upper inner quadrant of right breast. Dynamic MDCT images at baseline (A) and 1 (B), 3 (C), and 8 (D) minutes after contrast administration depict spiculated lesion with low enhancement 1 minute after contrast administration. Lesion was only one in study with value less than 90 H 1 minute after contrast administration; evaluation of time-attenuation curve, however, showed washout pattern.

 

Figure 24
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Fig. 12D 54-year-old woman with invasive ductal carcinoma in upper inner quadrant of right breast. Dynamic MDCT images at baseline (A) and 1 (B), 3 (C), and 8 (D) minutes after contrast administration depict spiculated lesion with low enhancement 1 minute after contrast administration. Lesion was only one in study with value less than 90 H 1 minute after contrast administration; evaluation of time-attenuation curve, however, showed washout pattern.

 

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